Reductive deamination of aromatic amines with nitric oxide (NO)

Takashi Itoh, Yûji Matsuya, Kazuhiro Nagata, Akio Ohsawa*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Aromatic amines were treated with nitric oxide in tetrahydrofuran or chloroform under argon atmosphere to afford deaminated aromatic compounds in good yields. The reaction is suggested to proceed via aryl radicals, which are supposed to be formed by reduction of aryldiazonium salts with NO.

Original languageEnglish
Pages (from-to)4165-4168
Number of pages4
JournalTetrahedron Letters
Volume37
Issue number24
DOIs
StatePublished - 1996/06/10

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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