Reaction of amides with nitric oxide (NO)

Takashi Itoh; Kazuhiro Nagata; Yûji Matsuya; Michiko Miyazaki; Akio Ohsawa

doi:10.1016/S0040-4039(97)01074-5

Reaction of amides with nitric oxide (NO)

Takashi Itoh, Kazuhiro Nagata, Yûji Matsuya, Michiko Miyazaki, Akio Ohsawa^*

^*Corresponding author for this work

Synthetic and Medicinal Chemistry

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

Amides were allowed to react with nitric oxide in aprotic and non- ethereal solvents to give the corresponding N-nitroso derivatives. The reaction was accelerated by addition of oxygen. The solvent effect revealed that the reaction did not proceed in the presence of protic media.

Original language	English
Pages (from-to)	5017-5020
Number of pages	4
Journal	Tetrahedron Letters
Volume	38
Issue number	28
DOIs	https://doi.org/10.1016/S0040-4039(97)01074-5
State	Published - 1997/07/14

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Reaction of amides with nitric oxide (NO)",

abstract = "Amides were allowed to react with nitric oxide in aprotic and non- ethereal solvents to give the corresponding N-nitroso derivatives. The reaction was accelerated by addition of oxygen. The solvent effect revealed that the reaction did not proceed in the presence of protic media.",

author = "Takashi Itoh and Kazuhiro Nagata and Y{\^u}ji Matsuya and Michiko Miyazaki and Akio Ohsawa",

year = "1997",

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T1 - Reaction of amides with nitric oxide (NO)

AU - Itoh, Takashi

AU - Nagata, Kazuhiro

AU - Matsuya, Yûji

AU - Miyazaki, Michiko

AU - Ohsawa, Akio

PY - 1997/7/14

Y1 - 1997/7/14

N2 - Amides were allowed to react with nitric oxide in aprotic and non- ethereal solvents to give the corresponding N-nitroso derivatives. The reaction was accelerated by addition of oxygen. The solvent effect revealed that the reaction did not proceed in the presence of protic media.

AB - Amides were allowed to react with nitric oxide in aprotic and non- ethereal solvents to give the corresponding N-nitroso derivatives. The reaction was accelerated by addition of oxygen. The solvent effect revealed that the reaction did not proceed in the presence of protic media.

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U2 - 10.1016/S0040-4039(97)01074-5

DO - 10.1016/S0040-4039(97)01074-5

M3 - 学術論文

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SP - 5017

EP - 5020

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 28

ER -

Reaction of amides with nitric oxide (NO)

Abstract

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