Abstract
A quartz crystal resonator was used for gelation monitoring and applied to the determination of fibrinogen concentration. The system consists of a 9-MHz AT-cut quartz crystal with a well- type cell, oscillator, frequency counter and microcomputer. The gelation time of fibrinogen on mixing with thrombin solution was determined by computer processing. The effect of temperature was avoided by the addition of aluminium oxide particles to the thrombin solution. The gelation time obtained in this system showed good linearity with fibrinogen concentration over the range 50-500 mg d l-1.
| Original language | English |
|---|---|
| Pages (from-to) | 321-326 |
| Number of pages | 6 |
| Journal | Analytica Chimica Acta |
| Volume | 217 |
| Issue number | C |
| DOIs | |
| State | Published - 1989 |
ASJC Scopus subject areas
- Analytical Chemistry
- Biochemistry
- Environmental Chemistry
- Spectroscopy