Precancerous lesions of the pancreas

Giuseppe Zamboni; Kenichi Hirabayashi; Paola Castelli; Anne Marie Lennon

doi:10.1016/j.bpg.2013.04.001

Precancerous lesions of the pancreas

Giuseppe Zamboni^*, Kenichi Hirabayashi, Paola Castelli, Anne Marie Lennon

^*Corresponding author for this work

Diagnostic Pathology

Research output: Contribution to journal › Review article › peer-review

59 Scopus citations

Abstract

Pancreatic cancer has a very poor prognosis, with a five year survival of only 5%. New studies have shown that it takes over 11 years for cells to develop invasive capability. This provides an opportunity to intervene if precursor lesions can be detected. This paper reviews the molecular, pathological, clinical findings and management of pancreatic intraepithelial neoplasia (PanIN), intraductal pancreatic mucinous neoplasm (IPMN) and mucinous cystic neoplasm (MCN), three precursor lesions which can give rise to invasive carcinoma of the pancreas.

Original language	English
Pages (from-to)	299-322
Number of pages	24
Journal	Best Practice and Research: Clinical Gastroenterology
Volume	27
Issue number	2
DOIs	https://doi.org/10.1016/j.bpg.2013.04.001
State	Published - 2013/04

Keywords

Pancreas
Pancreatic cancer
Pancreatic neoplasms
Pathology
Precancerous lesions

ASJC Scopus subject areas

Gastroenterology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.bpg.2013.04.001

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title = "Precancerous lesions of the pancreas",

abstract = "Pancreatic cancer has a very poor prognosis, with a five year survival of only 5%. New studies have shown that it takes over 11 years for cells to develop invasive capability. This provides an opportunity to intervene if precursor lesions can be detected. This paper reviews the molecular, pathological, clinical findings and management of pancreatic intraepithelial neoplasia (PanIN), intraductal pancreatic mucinous neoplasm (IPMN) and mucinous cystic neoplasm (MCN), three precursor lesions which can give rise to invasive carcinoma of the pancreas.",

keywords = "Pancreas, Pancreatic cancer, Pancreatic neoplasms, Pathology, Precancerous lesions",

author = "Giuseppe Zamboni and Kenichi Hirabayashi and Paola Castelli and Lennon, {Anne Marie}",

year = "2013",

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doi = "10.1016/j.bpg.2013.04.001",

language = "英語",

volume = "27",

pages = "299--322",

journal = "Best Practice and Research: Clinical Gastroenterology",

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TY - JOUR

T1 - Precancerous lesions of the pancreas

AU - Zamboni, Giuseppe

AU - Hirabayashi, Kenichi

AU - Castelli, Paola

AU - Lennon, Anne Marie

PY - 2013/4

Y1 - 2013/4

N2 - Pancreatic cancer has a very poor prognosis, with a five year survival of only 5%. New studies have shown that it takes over 11 years for cells to develop invasive capability. This provides an opportunity to intervene if precursor lesions can be detected. This paper reviews the molecular, pathological, clinical findings and management of pancreatic intraepithelial neoplasia (PanIN), intraductal pancreatic mucinous neoplasm (IPMN) and mucinous cystic neoplasm (MCN), three precursor lesions which can give rise to invasive carcinoma of the pancreas.

AB - Pancreatic cancer has a very poor prognosis, with a five year survival of only 5%. New studies have shown that it takes over 11 years for cells to develop invasive capability. This provides an opportunity to intervene if precursor lesions can be detected. This paper reviews the molecular, pathological, clinical findings and management of pancreatic intraepithelial neoplasia (PanIN), intraductal pancreatic mucinous neoplasm (IPMN) and mucinous cystic neoplasm (MCN), three precursor lesions which can give rise to invasive carcinoma of the pancreas.

KW - Pancreas

KW - Pancreatic cancer

KW - Pancreatic neoplasms

KW - Pathology

KW - Precancerous lesions

UR - http://www.scopus.com/inward/record.url?scp=84879788056&partnerID=8YFLogxK

U2 - 10.1016/j.bpg.2013.04.001

DO - 10.1016/j.bpg.2013.04.001

M3 - 総説

AN - SCOPUS:84879788056

SN - 1521-6918

VL - 27

SP - 299

EP - 322

JO - Best Practice and Research: Clinical Gastroenterology

JF - Best Practice and Research: Clinical Gastroenterology

IS - 2

ER -

Precancerous lesions of the pancreas

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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