Abstract
Here we report a new class of 1,8-naphthyridine derivatives, 2-amino-7-(3,4-dimethoxyphenyl)-1,8-naphthyridine, 2-amino-7-(3,4-dihydroxy phenyl)-1,8-naphthyridine, 2-amino-(5,6-dimethoxy-1 H-indenyl [2,3-b])-1,8-naphthyridine, and 2-amino-(5,6-dihydroxy-1 H-indenyl [2,3-b])-1,8- naphthyridine. All of these compounds were synthesized via naphthyridine-ring forming reaction with 2,6-diaminopyridine-3-carboxaldehyde as a key step. The two dimethoxy derivatives showed predominant fluorescent emission around 400 nm in MeCN. Cyclic voltammetry of the two dihydroxy derivatives in phosphate buffer showed oxidation potentials of 0.2~0.25 V vs. Ag/AgCl.
Original language | English |
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Pages (from-to) | 411-415 |
Number of pages | 5 |
Journal | Heterocycles |
Volume | 79 |
Issue number | C |
DOIs | |
State | Published - 2009 |
Keywords
- Electrochemistry
- Hydrogen Bonding
- Naphthyridine Denvative
- Photochemistry
- Ring-Forming Reaction
ASJC Scopus subject areas
- Analytical Chemistry
- Pharmacology
- Organic Chemistry