Pharmacological and Device-Based Intervention for Preventing Heart Failure After Acute Myocardial Infarction ― A Clinical Review ―

Yuichi Saito*, Yoshio Kobayashi, Kenichi Tsujita, Koichiro Kuwahara, Yuji Ikari, Hiroyuki Tsutsui, Koichiro Kinugawa, Ken Kozuma

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

In patients with acute myocardial infarction (MI), heart failure (HF) is one of the most common complications that is associated with a significant burden of mortality and healthcare resources. The clinical benefits of key HF drugs, the so-called “4 pillars” or “fantastic 4”, namely β-blockers, mineralocorticoid receptor antagonists, angiotensin receptor-neprilysin inhibitor, and sodium-glucose cotransporter 2 inhibitors, have been established in patients with HF with reduced ejection fraction, whereas the effects of these drugs are not comprehensively appreciated in patients with acute MI. This review summarizes current evidence on pharmacological and device-based interventions for preventing HF after acute MI.

Original languageEnglish
Pages (from-to)1727-1736
Number of pages10
JournalCirculation Journal
Volume88
Issue number11
DOIs
StatePublished - 2024/11

Keywords

  • Acute myocardial infarction
  • Heart failure
  • Medication

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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