TY - JOUR
T1 - Optimizing the Application of Surgery for Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 10]
AU - Rodrigues-Pinto, Ricardo
AU - Montenegro, Thiago S.
AU - Davies, Benjamin M.
AU - Kato, So
AU - Kawaguchi, Yoshiharu
AU - Ito, Manabu
AU - Zileli, Mehmet
AU - Kwon, Brian K.
AU - Fehlings, Michael G.
AU - Koljonen, Paul A.
AU - Kurpad, Shekar N.
AU - Guest, James D.
AU - Aarabi, Bizhan
AU - Rahimi-Movaghar, Vafa
AU - Wilson, Jefferson R.
AU - Kotter, Mark R.N.
AU - Harrop, James S.
N1 - Publisher Copyright:
© The Author(s) 2021.
PY - 2022/2
Y1 - 2022/2
N2 - Study Design: Literature Review (Narrative). Objective: To introduce the number 10 research priority for Degenerative Cervical Myelopathy: Individualizing Surgery. Methods: This article summarizes the current recommendations and indications for surgery, including how known prognostic factors such as injury time, age, disease severity, and associated comorbidities impact surgical outcome. It also considers key areas of uncertainty that should be the focus of future research. Results: While a small proportion of conservatively managed patients may remain stable, the majority will deteriorate over time. To date, surgical decompression is the mainstay of treatment, able to halt disease progression and improve neurologic function and quality of life for most patients. Whilst this recognition has led to recommendations on when to offer surgery, there remain many uncertainties including the type of surgery, or timing in milder and/or asymptomatic cases. Their clarification has the potential to transform outcomes, by ensuring surgery offers each individual its maximum benefit. Conclusion: Developing the evidence to better guide surgical decision-making at the individual patient level is a research priority for Degenerative Cervical Myelopathy.
AB - Study Design: Literature Review (Narrative). Objective: To introduce the number 10 research priority for Degenerative Cervical Myelopathy: Individualizing Surgery. Methods: This article summarizes the current recommendations and indications for surgery, including how known prognostic factors such as injury time, age, disease severity, and associated comorbidities impact surgical outcome. It also considers key areas of uncertainty that should be the focus of future research. Results: While a small proportion of conservatively managed patients may remain stable, the majority will deteriorate over time. To date, surgical decompression is the mainstay of treatment, able to halt disease progression and improve neurologic function and quality of life for most patients. Whilst this recognition has led to recommendations on when to offer surgery, there remain many uncertainties including the type of surgery, or timing in milder and/or asymptomatic cases. Their clarification has the potential to transform outcomes, by ensuring surgery offers each individual its maximum benefit. Conclusion: Developing the evidence to better guide surgical decision-making at the individual patient level is a research priority for Degenerative Cervical Myelopathy.
KW - cervical spine
KW - cervical spondylotic myelopathy
KW - degenerative cervical myelopathy
KW - myelopathy
KW - nontraumatic spinal cord injury
KW - spondylosis
UR - http://www.scopus.com/inward/record.url?scp=85125767525&partnerID=8YFLogxK
U2 - 10.1177/21925682211062494
DO - 10.1177/21925682211062494
M3 - 学術論文
C2 - 35174733
AN - SCOPUS:85125767525
SN - 2192-5682
VL - 12
SP - 147S-158S
JO - Global Spine Journal
JF - Global Spine Journal
IS - 1
ER -