@inproceedings{5f42de0ebfdb4143b377f9c8527de694,
title = "Non-invasive blood glucose measurement using fixed-wavelength quantum cascade lasers",
abstract = "An ATR measurement system composed of hollow optical fibers, a trapezoid multi-reflection prism, and a couple of fixed-wavelength QCLs emitting different wavelengths is proposed for non-invasive measurement of blood glucose. To choose a wavelength combination that is appropriate for measurement of glucose absorption, firstly absorption spectra of human lip mucosa measured by using an FT-IR-based ATR system are investigated. As a result, two wavelengths, 1152 cm-1 that coincides with an absorption peak of glucose, and 1186 cm-1 where the glucose absorption becomes minimum are chosen. From numerical simulation using spectral absorptions measured by the FT-IR system, it is found that the differential absorption between the above wavelengths shows a good correlation to blood glucose levels. Finally in-vivo measurement using the ATR system equipped with two single-wavelength QCLs is performed and it is found that the measured optical absorption follows the blood glucose well.",
keywords = "ATR spectroscopy, Blood glucose, Hollow optical fiber, Quantum cascade laser",
author = "T. Koyama and S. Kino and Y. Matsuura",
note = "Publisher Copyright: {\textcopyright} COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.; Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIX 2019 ; Conference date: 02-02-2019 Through 03-02-2019",
year = "2019",
doi = "10.1117/12.2508200",
language = "英語",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Israel Gannot and Israel Gannot",
booktitle = "Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIX",
}