Non-alcoholic fatty liver disease satisfactorily treated with traditional Japanese kampo medicine

Yutaka Shimada; Makoto Fujimoto; Tatsuya Nogami; Hidetoshi Watari; Hideyuki Kitahara; Hiroki Misawa; Yoshiyuki Kimbara

doi:10.1002/tkm2.1083

Non-alcoholic fatty liver disease satisfactorily treated with traditional Japanese kampo medicine

Yutaka Shimada, Makoto Fujimoto, Tatsuya Nogami, Hidetoshi Watari, Hideyuki Kitahara, Hiroki Misawa, Yoshiyuki Kimbara

Japanese Oriental Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Case: An obese 17-year-old male patient with right hemiparesis secondary to cerebral infarction presented for kampo treatment. The hemiparesis and resultant lack of exercise had led to an increase in bodyweight. Serum alanine aminotransferase (ALT) was elevated and abdominal ultrasound identified fatty liver. The patient was diagnosed with non-alcoholic fatty liver disease (NAFLD). Aspirin and tocopherol acetate (vitamin E), previously prescribed, were continued, and kampo medicines were prescribed. Outcome(s): Two years and 6 months after the initial visit, we prescribed keishikashakuyakuto (Gui Zhi Jia Shao Yao Tang) extract, in addition to keishibukuryogan (Gui Zhi Fu Ling Wan) extract. Thereafter, serum ALT gradually decreased, despite no significant change in bodyweight or blood platelet count. Conclusion(s): Kampo medicine may be effective for the treatment of NAFLD.Copyright © 2017 Japan Society for Oriental Medicine and Medical and Pharmaceutical Society for WAKAN-YAKU

Original language	Japanese
Pages (from-to)	56-60
Number of pages	5
Journal	Traditional & Kampo Medicine
Volume	5
Issue number	1
DOIs	https://doi.org/10.1002/tkm2.1083
State	Published - 2018/04

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10.1002/tkm2.1083

Cite this

@article{ca57cc7fd67d4265bf33da2833263ca5,

title = "Non-alcoholic fatty liver disease satisfactorily treated with traditional Japanese kampo medicine",

abstract = "Case: An obese 17-year-old male patient with right hemiparesis secondary to cerebral infarction presented for kampo treatment. The hemiparesis and resultant lack of exercise had led to an increase in bodyweight. Serum alanine aminotransferase (ALT) was elevated and abdominal ultrasound identified fatty liver. The patient was diagnosed with non-alcoholic fatty liver disease (NAFLD). Aspirin and tocopherol acetate (vitamin E), previously prescribed, were continued, and kampo medicines were prescribed. Outcome(s): Two years and 6 months after the initial visit, we prescribed keishikashakuyakuto (Gui Zhi Jia Shao Yao Tang) extract, in addition to keishibukuryogan (Gui Zhi Fu Ling Wan) extract. Thereafter, serum ALT gradually decreased, despite no significant change in bodyweight or blood platelet count. Conclusion(s): Kampo medicine may be effective for the treatment of NAFLD.Copyright {\textcopyright} 2017 Japan Society for Oriental Medicine and Medical and Pharmaceutical Society for WAKAN-YAKU",

author = "Yutaka Shimada and Makoto Fujimoto and Tatsuya Nogami and Hidetoshi Watari and Hideyuki Kitahara and Hiroki Misawa and Yoshiyuki Kimbara",

year = "2018",

month = apr,

doi = "10.1002/tkm2.1083",

language = "日本",

volume = "5",

pages = "56--60",

journal = "Traditional & Kampo Medicine",

issn = "2053-4515",

publisher = "John Wiley and Sons Inc.",

number = "1",

}

TY - JOUR

T1 - Non-alcoholic fatty liver disease satisfactorily treated with traditional Japanese kampo medicine

AU - Shimada, Yutaka

AU - Fujimoto, Makoto

AU - Nogami, Tatsuya

AU - Watari, Hidetoshi

AU - Kitahara, Hideyuki

AU - Misawa, Hiroki

AU - Kimbara, Yoshiyuki

PY - 2018/4

Y1 - 2018/4

N2 - Case: An obese 17-year-old male patient with right hemiparesis secondary to cerebral infarction presented for kampo treatment. The hemiparesis and resultant lack of exercise had led to an increase in bodyweight. Serum alanine aminotransferase (ALT) was elevated and abdominal ultrasound identified fatty liver. The patient was diagnosed with non-alcoholic fatty liver disease (NAFLD). Aspirin and tocopherol acetate (vitamin E), previously prescribed, were continued, and kampo medicines were prescribed. Outcome(s): Two years and 6 months after the initial visit, we prescribed keishikashakuyakuto (Gui Zhi Jia Shao Yao Tang) extract, in addition to keishibukuryogan (Gui Zhi Fu Ling Wan) extract. Thereafter, serum ALT gradually decreased, despite no significant change in bodyweight or blood platelet count. Conclusion(s): Kampo medicine may be effective for the treatment of NAFLD.Copyright © 2017 Japan Society for Oriental Medicine and Medical and Pharmaceutical Society for WAKAN-YAKU

AB - Case: An obese 17-year-old male patient with right hemiparesis secondary to cerebral infarction presented for kampo treatment. The hemiparesis and resultant lack of exercise had led to an increase in bodyweight. Serum alanine aminotransferase (ALT) was elevated and abdominal ultrasound identified fatty liver. The patient was diagnosed with non-alcoholic fatty liver disease (NAFLD). Aspirin and tocopherol acetate (vitamin E), previously prescribed, were continued, and kampo medicines were prescribed. Outcome(s): Two years and 6 months after the initial visit, we prescribed keishikashakuyakuto (Gui Zhi Jia Shao Yao Tang) extract, in addition to keishibukuryogan (Gui Zhi Fu Ling Wan) extract. Thereafter, serum ALT gradually decreased, despite no significant change in bodyweight or blood platelet count. Conclusion(s): Kampo medicine may be effective for the treatment of NAFLD.Copyright © 2017 Japan Society for Oriental Medicine and Medical and Pharmaceutical Society for WAKAN-YAKU

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DO - 10.1002/tkm2.1083

M3 - 学術論文

SN - 2053-4515

VL - 5

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EP - 60

JO - Traditional & Kampo Medicine

JF - Traditional & Kampo Medicine

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