Nickel(II) bis(isatin thiosemicarbazone) complexes induced apoptosis through mitochondrial signaling pathway and G0/G1 cell cycle arrest in IM-9 cells

Keyphrases

• Induced Apoptosis 100%
• Mitochondrial Pathway 100%
• Nickel(II) 100%
• G1 Cell Cycle Arrest 100%
• Thiosemicarbazone 100%
• Isatin 100%
• U937 66%
• Cytotoxic Properties 66%
• Liver 33%
• Cancer Cells 33%
• X-ray Diffraction Method 33%
• Concentration-dependent 33%
• Western Blot Analysis 33%
• IC50 33%
• Apoptotic Cell Death 33%
• HepG2 33%
• B-cell Lymphoma 33%
• Cisplatin 33%
• Doxorubicin 33%
• Single Crystal X-ray Diffraction (SCXRD) 33%
• Anticancer Drugs 33%
• Caspase-3 33%
• Histiocytic Lymphoma 33%
• Cytochrome c (Cyt c) 33%
• Biological Characteristics 33%
• Myeloma 33%
• Protein Release 33%
• Novel Complex 33%
• Circular Form 33%
• Supercoiled DNA 33%
• Acute Monocytic Leukemia 33%
• Vero Cell Line 33%
• Daunorubicin 33%
• Bcl-2-associated X Protein 33%
• N-substituted Isatins 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Cytochrome C Oxidase 100%
• Nickel 100%
• Isatin 100%
• Thiosemicarbazone 100%
• IC50 14%
• Malignant Neoplasm 14%
• Western Blot 14%
• Cisplatin 14%
• Doxorubicin 14%
• Anticarcinogen 14%
• Caspase 3 14%
• Cytochrome C 14%
• Histiocytic Lymphoma 14%
• Daunorubicin 14%
• Thiosemicarbazone Derivative 14%
• Myeloma 14%
• Reduced Nicotinamide Adenine Dinucleotide Dehydrogenase (Ubiquinone) 14%
• Acute Monocytic Leukemia 14%
• Protein Bax 14%