New guaian-type sesquiterpene from Wikstroemia indica

Mamoru Kato; Yu Min He; Dya Fta Dibwe; Feng Li; Suresh Awale; Shigetoshi Kadota; Yasuhiro Tezuka

doi:10.1177/1934578x1400900101

New guaian-type sesquiterpene from Wikstroemia indica

Mamoru Kato, Yu Min He, Dya Fta Dibwe, Feng Li, Suresh Awale, Shigetoshi Kadota, Yasuhiro Tezuka^*

^*Corresponding author for this work

Section of Natural Products & Drug Discovery, Division of Medicinal Resources, Institute of Natural Medicine

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

From a MeOH extract of powdered roots of Wikstroemia indica, we isolated a new guaian-type sesquiterpene (1) and two known guaian-type sesquiterpenes [oleodaphnal (2), 1α,7α,10αH-guaia-4,11-dien-3-one (3 )], together with twelve known compounds: (+)-arctigenin, (+)-matairesinol, (+)-trachelogenin, (+)-nortrachelogenin, (+)-hinokinin, (+)-kusunokinin, 7-methoxycoumarin, 7-hydroxycoumarin (umbelliferone), daphnogitin, daphnoretin, salicifoliol, and (-)-pinoresinol. The structure of compound 1 was determined to be 4,10,11-guaiatrien-3-one-14-oic acid, by the analyses of spectral data.

Original language	English
Pages (from-to)	1-2
Number of pages	2
Journal	Natural Product Communications
Volume	9
Issue number	1
DOIs	https://doi.org/10.1177/1934578x1400900101
State	Published - 2014/01

Keywords

4,10,11-Guaiatrien-3-one-14- oic acid
Guaian-type sesquiterpene
Oleodaphnal
Wikstroemia indica

ASJC Scopus subject areas

Pharmacology
Plant Science
Drug Discovery
Complementary and alternative medicine

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10.1177/1934578x1400900101

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title = "New guaian-type sesquiterpene from Wikstroemia indica",

abstract = "From a MeOH extract of powdered roots of Wikstroemia indica, we isolated a new guaian-type sesquiterpene (1) and two known guaian-type sesquiterpenes [oleodaphnal (2), 1α,7α,10αH-guaia-4,11-dien-3-one (3 )], together with twelve known compounds: (+)-arctigenin, (+)-matairesinol, (+)-trachelogenin, (+)-nortrachelogenin, (+)-hinokinin, (+)-kusunokinin, 7-methoxycoumarin, 7-hydroxycoumarin (umbelliferone), daphnogitin, daphnoretin, salicifoliol, and (-)-pinoresinol. The structure of compound 1 was determined to be 4,10,11-guaiatrien-3-one-14-oic acid, by the analyses of spectral data.",

keywords = "4,10,11-Guaiatrien-3-one-14- oic acid, Guaian-type sesquiterpene, Oleodaphnal, Wikstroemia indica",

author = "Mamoru Kato and He, {Yu Min} and Dibwe, {Dya Fta} and Feng Li and Suresh Awale and Shigetoshi Kadota and Yasuhiro Tezuka",

year = "2014",

month = jan,

doi = "10.1177/1934578x1400900101",

language = "英語",

volume = "9",

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journal = "Natural Product Communications",

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T1 - New guaian-type sesquiterpene from Wikstroemia indica

AU - Kato, Mamoru

AU - He, Yu Min

AU - Dibwe, Dya Fta

AU - Li, Feng

AU - Awale, Suresh

AU - Kadota, Shigetoshi

AU - Tezuka, Yasuhiro

PY - 2014/1

Y1 - 2014/1

N2 - From a MeOH extract of powdered roots of Wikstroemia indica, we isolated a new guaian-type sesquiterpene (1) and two known guaian-type sesquiterpenes [oleodaphnal (2), 1α,7α,10αH-guaia-4,11-dien-3-one (3 )], together with twelve known compounds: (+)-arctigenin, (+)-matairesinol, (+)-trachelogenin, (+)-nortrachelogenin, (+)-hinokinin, (+)-kusunokinin, 7-methoxycoumarin, 7-hydroxycoumarin (umbelliferone), daphnogitin, daphnoretin, salicifoliol, and (-)-pinoresinol. The structure of compound 1 was determined to be 4,10,11-guaiatrien-3-one-14-oic acid, by the analyses of spectral data.

AB - From a MeOH extract of powdered roots of Wikstroemia indica, we isolated a new guaian-type sesquiterpene (1) and two known guaian-type sesquiterpenes [oleodaphnal (2), 1α,7α,10αH-guaia-4,11-dien-3-one (3 )], together with twelve known compounds: (+)-arctigenin, (+)-matairesinol, (+)-trachelogenin, (+)-nortrachelogenin, (+)-hinokinin, (+)-kusunokinin, 7-methoxycoumarin, 7-hydroxycoumarin (umbelliferone), daphnogitin, daphnoretin, salicifoliol, and (-)-pinoresinol. The structure of compound 1 was determined to be 4,10,11-guaiatrien-3-one-14-oic acid, by the analyses of spectral data.

KW - 4,10,11-Guaiatrien-3-one-14- oic acid

KW - Guaian-type sesquiterpene

KW - Oleodaphnal

KW - Wikstroemia indica

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DO - 10.1177/1934578x1400900101

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AN - SCOPUS:84894484127

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ER -

New guaian-type sesquiterpene from Wikstroemia indica

Abstract

Keywords

ASJC Scopus subject areas

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