Neurological improvement is associated with neck pain attenuation after surgery for cervical ossification of the posterior longitudinal ligament

Masao Koda; Toshitaka Yoshii; Satoru Egawa; Kenichiro Sakai; Kazuo Kusano; Yukihiro Nakagawa; Takashi Hirai; Kanichiro Wada; Keiichi Katsumi; Atsushi Kimura; Takeo Furuya; Satoshi Maki; Narihito Nagoshi; Kota Watanabe; Tsukasa Kanchiku; Yukitaka Nagamoto; Yasushi Oshima; Kei Ando; Hiroaki Nakashima; Masahiko Takahata; Kanji Mori; Hideaki Nakajima; Kazuma Murata; Shunji Matsunaga; Takashi Kaito; Kei Yamada; Sho Kobayashi; Satoshi Kato; Tetsuro Ohba; Satoshi Inami; Shunsuke Fujibayashi; Hiroyuki Katoh; Haruo Kanno; Hiroshi Takahashi; Kengo Fujii; Masayuki Miyagi; Gen Inoue; Masashi Takaso; Shiro Imagama; Yoshiharu Kawaguchi; Katsushi Takeshita; Masaya Nakamura; Morio Matsumoto; Atsushi Okawa; Masashi Yamazaki

doi:10.1038/s41598-021-91268-2

Neurological improvement is associated with neck pain attenuation after surgery for cervical ossification of the posterior longitudinal ligament

Masao Koda^*, Toshitaka Yoshii, Satoru Egawa, Kenichiro Sakai, Kazuo Kusano, Yukihiro Nakagawa, Takashi Hirai, Kanichiro Wada, Keiichi Katsumi, Atsushi Kimura, Takeo Furuya, Satoshi Maki, Narihito Nagoshi, Kota Watanabe, Tsukasa Kanchiku, Yukitaka Nagamoto, Yasushi Oshima, Kei Ando, Hiroaki Nakashima, Masahiko TakahataKanji Mori, Hideaki Nakajima, Kazuma Murata, Shunji Matsunaga, Takashi Kaito, Kei Yamada, Sho Kobayashi, Satoshi Kato, Tetsuro Ohba, Satoshi Inami, Shunsuke Fujibayashi, Hiroyuki Katoh, Haruo Kanno, Hiroshi Takahashi, Kengo Fujii, Masayuki Miyagi, Gen Inoue, Masashi Takaso, Shiro Imagama, Yoshiharu Kawaguchi, Katsushi Takeshita, Masaya Nakamura, Morio Matsumoto, Atsushi Okawa, Masashi Yamazaki

^*Corresponding author for this work

Orthopaedic Surgery

Research output: Contribution to journal › Article › peer-review

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Abstract

Although favourable surgical outcomes for myelopathy caused by cervical ossification of the posterior longitudinal ligament (OPLL) have been reported, factors significantly associated with post-operative neck pain attenuation still remain unclear. The primary aim of the present study was to determine factors significantly associated with post-operative neck pain attenuation in patients with cervical OPLL using a prospective multi-centre registry of surgically treated cervical OPLL. Significant postoperative neck pain reduction (50% reduction of neck pain) was achieved in 31.3% of patients. There was no significant difference in neck pain attenuation between surgical procedures. Statistical analyses with univariate analyses followed by stepwise logistic regression revealed neurological recovery as a factor having a significant positive association with post-operative neck pain attenuation (p = 0.04, odds ratio 5.68 (95% confidence interval: 1.27–22.2)). In conclusion, neurological recovery was an independent factor having a significant positive association with post-operative neck pain attenuation in patients with cervical myelopathy caused by OPLL who underwent cervical spine surgery.

Original language	English
Article number	11910
Journal	Scientific Reports
Volume	11
Issue number	1
DOIs	https://doi.org/10.1038/s41598-021-91268-2
State	Published - 2021/12

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Koda, M., Yoshii, T., Egawa, S., Sakai, K., Kusano, K., Nakagawa, Y., Hirai, T., Wada, K., Katsumi, K., Kimura, A., Furuya, T., Maki, S., Nagoshi, N., Watanabe, K., Kanchiku, T., Nagamoto, Y., Oshima, Y., Ando, K., Nakashima, H., ... Yamazaki, M. (2021). Neurological improvement is associated with neck pain attenuation after surgery for cervical ossification of the posterior longitudinal ligament. Scientific Reports, 11(1), Article 11910. https://doi.org/10.1038/s41598-021-91268-2

@article{c331ac6b27ec4d5c830e88885cc49ea2,

title = "Neurological improvement is associated with neck pain attenuation after surgery for cervical ossification of the posterior longitudinal ligament",

abstract = "Although favourable surgical outcomes for myelopathy caused by cervical ossification of the posterior longitudinal ligament (OPLL) have been reported, factors significantly associated with post-operative neck pain attenuation still remain unclear. The primary aim of the present study was to determine factors significantly associated with post-operative neck pain attenuation in patients with cervical OPLL using a prospective multi-centre registry of surgically treated cervical OPLL. Significant postoperative neck pain reduction (50% reduction of neck pain) was achieved in 31.3% of patients. There was no significant difference in neck pain attenuation between surgical procedures. Statistical analyses with univariate analyses followed by stepwise logistic regression revealed neurological recovery as a factor having a significant positive association with post-operative neck pain attenuation (p = 0.04, odds ratio 5.68 (95% confidence interval: 1.27–22.2)). In conclusion, neurological recovery was an independent factor having a significant positive association with post-operative neck pain attenuation in patients with cervical myelopathy caused by OPLL who underwent cervical spine surgery.",

author = "Masao Koda and Toshitaka Yoshii and Satoru Egawa and Kenichiro Sakai and Kazuo Kusano and Yukihiro Nakagawa and Takashi Hirai and Kanichiro Wada and Keiichi Katsumi and Atsushi Kimura and Takeo Furuya and Satoshi Maki and Narihito Nagoshi and Kota Watanabe and Tsukasa Kanchiku and Yukitaka Nagamoto and Yasushi Oshima and Kei Ando and Hiroaki Nakashima and Masahiko Takahata and Kanji Mori and Hideaki Nakajima and Kazuma Murata and Shunji Matsunaga and Takashi Kaito and Kei Yamada and Sho Kobayashi and Satoshi Kato and Tetsuro Ohba and Satoshi Inami and Shunsuke Fujibayashi and Hiroyuki Katoh and Haruo Kanno and Hiroshi Takahashi and Kengo Fujii and Masayuki Miyagi and Gen Inoue and Masashi Takaso and Shiro Imagama and Yoshiharu Kawaguchi and Katsushi Takeshita and Masaya Nakamura and Morio Matsumoto and Atsushi Okawa and Masashi Yamazaki",

note = "Publisher Copyright: {\textcopyright} 2021, The Author(s).",

year = "2021",

month = dec,

doi = "10.1038/s41598-021-91268-2",

language = "英語",

volume = "11",

journal = "Scientific Reports",

issn = "2045-2322",

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Koda, M, Yoshii, T, Egawa, S, Sakai, K, Kusano, K, Nakagawa, Y, Hirai, T, Wada, K, Katsumi, K, Kimura, A, Furuya, T, Maki, S, Nagoshi, N, Watanabe, K, Kanchiku, T, Nagamoto, Y, Oshima, Y, Ando, K, Nakashima, H, Takahata, M, Mori, K, Nakajima, H, Murata, K, Matsunaga, S, Kaito, T, Yamada, K, Kobayashi, S, Kato, S, Ohba, T, Inami, S, Fujibayashi, S, Katoh, H, Kanno, H, Takahashi, H, Fujii, K, Miyagi, M, Inoue, G, Takaso, M, Imagama, S, Kawaguchi, Y, Takeshita, K, Nakamura, M, Matsumoto, M, Okawa, A & Yamazaki, M 2021, 'Neurological improvement is associated with neck pain attenuation after surgery for cervical ossification of the posterior longitudinal ligament', Scientific Reports, vol. 11, no. 1, 11910. https://doi.org/10.1038/s41598-021-91268-2

TY - JOUR

T1 - Neurological improvement is associated with neck pain attenuation after surgery for cervical ossification of the posterior longitudinal ligament

AU - Koda, Masao

AU - Yoshii, Toshitaka

AU - Egawa, Satoru

AU - Sakai, Kenichiro

AU - Kusano, Kazuo

AU - Nakagawa, Yukihiro

AU - Hirai, Takashi

AU - Wada, Kanichiro

AU - Katsumi, Keiichi

AU - Kimura, Atsushi

AU - Furuya, Takeo

AU - Maki, Satoshi

AU - Nagoshi, Narihito

AU - Watanabe, Kota

AU - Kanchiku, Tsukasa

AU - Nagamoto, Yukitaka

AU - Oshima, Yasushi

AU - Ando, Kei

AU - Nakashima, Hiroaki

AU - Takahata, Masahiko

AU - Mori, Kanji

AU - Nakajima, Hideaki

AU - Murata, Kazuma

AU - Matsunaga, Shunji

AU - Kaito, Takashi

AU - Yamada, Kei

AU - Kobayashi, Sho

AU - Kato, Satoshi

AU - Ohba, Tetsuro

AU - Inami, Satoshi

AU - Fujibayashi, Shunsuke

AU - Katoh, Hiroyuki

AU - Kanno, Haruo

AU - Takahashi, Hiroshi

AU - Fujii, Kengo

AU - Miyagi, Masayuki

AU - Inoue, Gen

AU - Takaso, Masashi

AU - Imagama, Shiro

AU - Kawaguchi, Yoshiharu

AU - Takeshita, Katsushi

AU - Nakamura, Masaya

AU - Matsumoto, Morio

AU - Okawa, Atsushi

AU - Yamazaki, Masashi

PY - 2021/12

Y1 - 2021/12

N2 - Although favourable surgical outcomes for myelopathy caused by cervical ossification of the posterior longitudinal ligament (OPLL) have been reported, factors significantly associated with post-operative neck pain attenuation still remain unclear. The primary aim of the present study was to determine factors significantly associated with post-operative neck pain attenuation in patients with cervical OPLL using a prospective multi-centre registry of surgically treated cervical OPLL. Significant postoperative neck pain reduction (50% reduction of neck pain) was achieved in 31.3% of patients. There was no significant difference in neck pain attenuation between surgical procedures. Statistical analyses with univariate analyses followed by stepwise logistic regression revealed neurological recovery as a factor having a significant positive association with post-operative neck pain attenuation (p = 0.04, odds ratio 5.68 (95% confidence interval: 1.27–22.2)). In conclusion, neurological recovery was an independent factor having a significant positive association with post-operative neck pain attenuation in patients with cervical myelopathy caused by OPLL who underwent cervical spine surgery.

AB - Although favourable surgical outcomes for myelopathy caused by cervical ossification of the posterior longitudinal ligament (OPLL) have been reported, factors significantly associated with post-operative neck pain attenuation still remain unclear. The primary aim of the present study was to determine factors significantly associated with post-operative neck pain attenuation in patients with cervical OPLL using a prospective multi-centre registry of surgically treated cervical OPLL. Significant postoperative neck pain reduction (50% reduction of neck pain) was achieved in 31.3% of patients. There was no significant difference in neck pain attenuation between surgical procedures. Statistical analyses with univariate analyses followed by stepwise logistic regression revealed neurological recovery as a factor having a significant positive association with post-operative neck pain attenuation (p = 0.04, odds ratio 5.68 (95% confidence interval: 1.27–22.2)). In conclusion, neurological recovery was an independent factor having a significant positive association with post-operative neck pain attenuation in patients with cervical myelopathy caused by OPLL who underwent cervical spine surgery.

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U2 - 10.1038/s41598-021-91268-2

DO - 10.1038/s41598-021-91268-2

M3 - 学術論文

C2 - 34099784

AN - SCOPUS:85107601434

SN - 2045-2322

VL - 11

JO - Scientific Reports

JF - Scientific Reports

IS - 1

M1 - 11910

ER -

Neurological improvement is associated with neck pain attenuation after surgery for cervical ossification of the posterior longitudinal ligament

Abstract

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