Morphological relationship between serotonergic neurons and nitrergic neurons for electrolytes secretion in the submucous plexus of the guinea pig distal colon

Makoto Kadowaki; Hirofumi Kuramoto; Atsukazu Kuwahara

doi:10.1016/S0006-8993(99)01428-6

Morphological relationship between serotonergic neurons and nitrergic neurons for electrolytes secretion in the submucous plexus of the guinea pig distal colon

Makoto Kadowaki^*, Hirofumi Kuramoto, Atsukazu Kuwahara

^*Corresponding author for this work

Research Center for Pre-Disease Science

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

In the submucous plexus, double immunocytochemistry revealed that nitric oxide synthase (NOS)-immunoreactivity was found in both numerous nerve fibers and some nerve cell bodies, while 5-hydroxytryptamine (5-HT)-immunoreactivity was limited to many nerve fibers, but not any nerve cell bodies. About 30% of the total NOS positive neurons (978) had close or some contact with 5-HT positive nerve fiber, suggesting that NO may participate in the 5-HT-evoked chloride secretion.

Original language	English
Pages (from-to)	288-291
Number of pages	4
Journal	Brain Research
Volume	831
Issue number	1-2
DOIs	https://doi.org/10.1016/S0006-8993(99)01428-6
State	Published - 1999/06/12

Keywords

5-Hydroxytryptamine
Distal colon
Guinea pig
Immunocytochemistry
Nitric oxide
Submucous plexus

ASJC Scopus subject areas

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/S0006-8993(99)01428-6

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title = "Morphological relationship between serotonergic neurons and nitrergic neurons for electrolytes secretion in the submucous plexus of the guinea pig distal colon",

abstract = "In the submucous plexus, double immunocytochemistry revealed that nitric oxide synthase (NOS)-immunoreactivity was found in both numerous nerve fibers and some nerve cell bodies, while 5-hydroxytryptamine (5-HT)-immunoreactivity was limited to many nerve fibers, but not any nerve cell bodies. About 30% of the total NOS positive neurons (978) had close or some contact with 5-HT positive nerve fiber, suggesting that NO may participate in the 5-HT-evoked chloride secretion.",

keywords = "5-Hydroxytryptamine, Distal colon, Guinea pig, Immunocytochemistry, Nitric oxide, Submucous plexus",

author = "Makoto Kadowaki and Hirofumi Kuramoto and Atsukazu Kuwahara",

note = "Funding Information: The authors thank Dr. Paul R. Wade (The University of Wyoming) for reviewing the manuscript. This work was supported by Monbusyo International research grant, Salt foundation and Health Science Foundation to AK. ",

year = "1999",

month = jun,

day = "12",

doi = "10.1016/S0006-8993(99)01428-6",

language = "英語",

volume = "831",

pages = "288--291",

journal = "Brain Research",

issn = "0006-8993",

publisher = "Elsevier B.V.",

number = "1-2",

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TY - JOUR

T1 - Morphological relationship between serotonergic neurons and nitrergic neurons for electrolytes secretion in the submucous plexus of the guinea pig distal colon

AU - Kadowaki, Makoto

AU - Kuramoto, Hirofumi

AU - Kuwahara, Atsukazu

N1 - Funding Information: The authors thank Dr. Paul R. Wade (The University of Wyoming) for reviewing the manuscript. This work was supported by Monbusyo International research grant, Salt foundation and Health Science Foundation to AK.

PY - 1999/6/12

Y1 - 1999/6/12

N2 - In the submucous plexus, double immunocytochemistry revealed that nitric oxide synthase (NOS)-immunoreactivity was found in both numerous nerve fibers and some nerve cell bodies, while 5-hydroxytryptamine (5-HT)-immunoreactivity was limited to many nerve fibers, but not any nerve cell bodies. About 30% of the total NOS positive neurons (978) had close or some contact with 5-HT positive nerve fiber, suggesting that NO may participate in the 5-HT-evoked chloride secretion.

AB - In the submucous plexus, double immunocytochemistry revealed that nitric oxide synthase (NOS)-immunoreactivity was found in both numerous nerve fibers and some nerve cell bodies, while 5-hydroxytryptamine (5-HT)-immunoreactivity was limited to many nerve fibers, but not any nerve cell bodies. About 30% of the total NOS positive neurons (978) had close or some contact with 5-HT positive nerve fiber, suggesting that NO may participate in the 5-HT-evoked chloride secretion.

KW - 5-Hydroxytryptamine

KW - Distal colon

KW - Guinea pig

KW - Immunocytochemistry

KW - Nitric oxide

KW - Submucous plexus

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DO - 10.1016/S0006-8993(99)01428-6

M3 - 学術論文

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AN - SCOPUS:0033549243

SN - 0006-8993

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EP - 291

JO - Brain Research

JF - Brain Research

IS - 1-2

ER -

Morphological relationship between serotonergic neurons and nitrergic neurons for electrolytes secretion in the submucous plexus of the guinea pig distal colon

Abstract

Keywords

ASJC Scopus subject areas

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