Monitoring of cerebral hemodynamics using near-infrared spectroscopy during local intra-arterial thrombolysis: Case report

Hisashi Nagashima; Hiroshi Okudera; Shigeaki Kobayashi; Tomomi Iwashita

doi:10.1016/S0090-3019(97)00199-7

Monitoring of cerebral hemodynamics using near-infrared spectroscopy during local intra-arterial thrombolysis: Case report

Hisashi Nagashima, Hiroshi Okudera^*, Shigeaki Kobayashi, Tomomi Iwashita

^*Corresponding author for this work

Department of Patient Safety

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

BACKGROUND: The efficacy of continuous measuring of changes in regional cerebrovascular hemoglobin saturation during local intraarterial thrombolytic therapy for middle cerebral artery (MCA) occlusion is discussed. METHODS: To obtain real-time data on changing cerebral hemodynamics, near-infrared spectroscopy (NIRS) was used during recanalization of an occluded MCA branch. Changes in regional cerebrovascular hemoglobin saturation of the affected left frontal lobe were observed immediately after intraarterial injection of urokinase (UK). RESULTS: A steady increase in regional oxygen saturation (rSO2) was observed until recanalization was confirmed angiographically as a result of 300,000 IU of UK. CONCLUSIONS: Monitoring of cerebrovascular hemoglobin saturation by NIPS is a simple, noninvasive technique suggesting its potential for intraoperative monitoring during interventional neuroradiologic procedures.

Original language	English
Pages (from-to)	420-424
Number of pages	5
Journal	Surgical Neurology
Volume	49
Issue number	4
DOIs	https://doi.org/10.1016/S0090-3019(97)00199-7
State	Published - 1998/04

Keywords

Cerebral ischemia
Fibrinolytic therapy
Monitoring
Near-infrared spectroscopy
Urokinase

ASJC Scopus subject areas

Surgery
Clinical Neurology

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10.1016/S0090-3019(97)00199-7

Cite this

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title = "Monitoring of cerebral hemodynamics using near-infrared spectroscopy during local intra-arterial thrombolysis: Case report",

abstract = "BACKGROUND: The efficacy of continuous measuring of changes in regional cerebrovascular hemoglobin saturation during local intraarterial thrombolytic therapy for middle cerebral artery (MCA) occlusion is discussed. METHODS: To obtain real-time data on changing cerebral hemodynamics, near-infrared spectroscopy (NIRS) was used during recanalization of an occluded MCA branch. Changes in regional cerebrovascular hemoglobin saturation of the affected left frontal lobe were observed immediately after intraarterial injection of urokinase (UK). RESULTS: A steady increase in regional oxygen saturation (rSO2) was observed until recanalization was confirmed angiographically as a result of 300,000 IU of UK. CONCLUSIONS: Monitoring of cerebrovascular hemoglobin saturation by NIPS is a simple, noninvasive technique suggesting its potential for intraoperative monitoring during interventional neuroradiologic procedures.",

keywords = "Cerebral ischemia, Fibrinolytic therapy, Monitoring, Near-infrared spectroscopy, Urokinase",

author = "Hisashi Nagashima and Hiroshi Okudera and Shigeaki Kobayashi and Tomomi Iwashita",

year = "1998",

month = apr,

doi = "10.1016/S0090-3019(97)00199-7",

language = "英語",

volume = "49",

pages = "420--424",

journal = "Surgical Neurology",

issn = "0090-3019",

publisher = "Elsevier B.V.",

number = "4",

}

TY - JOUR

T1 - Monitoring of cerebral hemodynamics using near-infrared spectroscopy during local intra-arterial thrombolysis

T2 - Case report

AU - Nagashima, Hisashi

AU - Okudera, Hiroshi

AU - Kobayashi, Shigeaki

AU - Iwashita, Tomomi

PY - 1998/4

Y1 - 1998/4

N2 - BACKGROUND: The efficacy of continuous measuring of changes in regional cerebrovascular hemoglobin saturation during local intraarterial thrombolytic therapy for middle cerebral artery (MCA) occlusion is discussed. METHODS: To obtain real-time data on changing cerebral hemodynamics, near-infrared spectroscopy (NIRS) was used during recanalization of an occluded MCA branch. Changes in regional cerebrovascular hemoglobin saturation of the affected left frontal lobe were observed immediately after intraarterial injection of urokinase (UK). RESULTS: A steady increase in regional oxygen saturation (rSO2) was observed until recanalization was confirmed angiographically as a result of 300,000 IU of UK. CONCLUSIONS: Monitoring of cerebrovascular hemoglobin saturation by NIPS is a simple, noninvasive technique suggesting its potential for intraoperative monitoring during interventional neuroradiologic procedures.

AB - BACKGROUND: The efficacy of continuous measuring of changes in regional cerebrovascular hemoglobin saturation during local intraarterial thrombolytic therapy for middle cerebral artery (MCA) occlusion is discussed. METHODS: To obtain real-time data on changing cerebral hemodynamics, near-infrared spectroscopy (NIRS) was used during recanalization of an occluded MCA branch. Changes in regional cerebrovascular hemoglobin saturation of the affected left frontal lobe were observed immediately after intraarterial injection of urokinase (UK). RESULTS: A steady increase in regional oxygen saturation (rSO2) was observed until recanalization was confirmed angiographically as a result of 300,000 IU of UK. CONCLUSIONS: Monitoring of cerebrovascular hemoglobin saturation by NIPS is a simple, noninvasive technique suggesting its potential for intraoperative monitoring during interventional neuroradiologic procedures.

KW - Cerebral ischemia

KW - Fibrinolytic therapy

KW - Monitoring

KW - Near-infrared spectroscopy

KW - Urokinase

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U2 - 10.1016/S0090-3019(97)00199-7

DO - 10.1016/S0090-3019(97)00199-7

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AN - SCOPUS:0032054785

SN - 0090-3019

VL - 49

SP - 420

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JO - Surgical Neurology

JF - Surgical Neurology

IS - 4

ER -

Monitoring of cerebral hemodynamics using near-infrared spectroscopy during local intra-arterial thrombolysis: Case report

Abstract

Keywords

ASJC Scopus subject areas

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