Longitudinal MRI study of the midline brain regions in first-episode schizophrenia

Tsutomu Takahashi; Kazue Nakamura; Eiji Ikeda; Atsushi Furuichi; Mikio Kido; Yumiko Nakamura; Yasuhiro Kawasaki; Kyo Noguchi; Hikaru Seto; Michio Suzuki

doi:10.1016/j.pscychresns.2012.12.001

Longitudinal MRI study of the midline brain regions in first-episode schizophrenia

Tsutomu Takahashi^*, Kazue Nakamura, Eiji Ikeda, Atsushi Furuichi, Mikio Kido, Yumiko Nakamura, Yasuhiro Kawasaki, Kyo Noguchi, Hikaru Seto, Michio Suzuki

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

This magnetic resonance imaging (MRI) study investigated the prevalence and size of the adhesio interthalamica (AI) and cavum septi pellucidi (CSP) in 64 first-episode schizophrenia patients and 64 controls, of whom longitudinal data were available for 20 patients and 21 controls. The AI was shorter in the patients and showed longitudinal decline in both groups; there was also a trend for AI atrophy to correlate with negative symptoms. The CSP showed no group difference. These results suggest a role for the AI as a possible neurodevelopmental marker of schizophrenia.

Original language	English
Pages (from-to)	150-153
Number of pages	4
Journal	Psychiatry Research - Neuroimaging
Volume	212
Issue number	2
DOIs	https://doi.org/10.1016/j.pscychresns.2012.12.001
State	Published - 2013/05/30

Keywords

Adhesio interthalamica
Cavum septi pellucidi
Magnetic resonance imaging

ASJC Scopus subject areas

Neuroscience (miscellaneous)
Radiology Nuclear Medicine and imaging
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.pscychresns.2012.12.001

Cite this

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title = "Longitudinal MRI study of the midline brain regions in first-episode schizophrenia",

abstract = "This magnetic resonance imaging (MRI) study investigated the prevalence and size of the adhesio interthalamica (AI) and cavum septi pellucidi (CSP) in 64 first-episode schizophrenia patients and 64 controls, of whom longitudinal data were available for 20 patients and 21 controls. The AI was shorter in the patients and showed longitudinal decline in both groups; there was also a trend for AI atrophy to correlate with negative symptoms. The CSP showed no group difference. These results suggest a role for the AI as a possible neurodevelopmental marker of schizophrenia.",

keywords = "Adhesio interthalamica, Cavum septi pellucidi, Magnetic resonance imaging",

author = "Tsutomu Takahashi and Kazue Nakamura and Eiji Ikeda and Atsushi Furuichi and Mikio Kido and Yumiko Nakamura and Yasuhiro Kawasaki and Kyo Noguchi and Hikaru Seto and Michio Suzuki",

note = "Funding Information: This research was supported in part by the Grants-in-Aid for Scientific Research (C) (Nos. 22591275 and 24591699 ) from the Japanese Society for the Promotion of Science, Health and Labor Sciences Research Grants (Comprehensive Research on Disability, Health and Welfare, H23-Seishin-Ippan-002 and H23-Seishin-Ippan-009), and a Research Grant from the JSPS Asian Core Program. ",

year = "2013",

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doi = "10.1016/j.pscychresns.2012.12.001",

language = "英語",

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AU - Takahashi, Tsutomu

AU - Nakamura, Kazue

AU - Ikeda, Eiji

AU - Furuichi, Atsushi

AU - Kido, Mikio

AU - Nakamura, Yumiko

AU - Kawasaki, Yasuhiro

AU - Noguchi, Kyo

AU - Seto, Hikaru

AU - Suzuki, Michio

N1 - Funding Information: This research was supported in part by the Grants-in-Aid for Scientific Research (C) (Nos. 22591275 and 24591699 ) from the Japanese Society for the Promotion of Science, Health and Labor Sciences Research Grants (Comprehensive Research on Disability, Health and Welfare, H23-Seishin-Ippan-002 and H23-Seishin-Ippan-009), and a Research Grant from the JSPS Asian Core Program.

PY - 2013/5/30

Y1 - 2013/5/30

N2 - This magnetic resonance imaging (MRI) study investigated the prevalence and size of the adhesio interthalamica (AI) and cavum septi pellucidi (CSP) in 64 first-episode schizophrenia patients and 64 controls, of whom longitudinal data were available for 20 patients and 21 controls. The AI was shorter in the patients and showed longitudinal decline in both groups; there was also a trend for AI atrophy to correlate with negative symptoms. The CSP showed no group difference. These results suggest a role for the AI as a possible neurodevelopmental marker of schizophrenia.

AB - This magnetic resonance imaging (MRI) study investigated the prevalence and size of the adhesio interthalamica (AI) and cavum septi pellucidi (CSP) in 64 first-episode schizophrenia patients and 64 controls, of whom longitudinal data were available for 20 patients and 21 controls. The AI was shorter in the patients and showed longitudinal decline in both groups; there was also a trend for AI atrophy to correlate with negative symptoms. The CSP showed no group difference. These results suggest a role for the AI as a possible neurodevelopmental marker of schizophrenia.

KW - Adhesio interthalamica

KW - Cavum septi pellucidi

KW - Magnetic resonance imaging

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U2 - 10.1016/j.pscychresns.2012.12.001

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AN - SCOPUS:84876800106

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JO - Psychiatry Research - Neuroimaging

JF - Psychiatry Research - Neuroimaging

IS - 2

ER -

Longitudinal MRI study of the midline brain regions in first-episode schizophrenia

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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