Living-donor lobar lung transplantation for pulmonary alveolar proteinosis in an adult: Report of a case

Tsutomu Tagawa; Naoya Yamasaki; Tomoshi Tsuchiya; Takuro Miyazaki; Kei Matsuki; Yoshiko Tsuchihashi; Konosuke Morimoto; Takeshi Nagayasu

doi:10.1007/s00595-010-4411-0

Living-donor lobar lung transplantation for pulmonary alveolar proteinosis in an adult: Report of a case

Tsutomu Tagawa^*, Naoya Yamasaki, Tomoshi Tsuchiya, Takuro Miyazaki, Kei Matsuki, Yoshiko Tsuchihashi, Konosuke Morimoto, Takeshi Nagayasu

^*Corresponding author for this work

Thoracic Surgery

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

A 43-year-old woman with pulmonary alveolar proteinosis (PAP) was successfully treated with livingdonor lobar lung transplantation (LDLLT). The patient's PAP had been diagnosed at age 35. She had been treated with repeated bronchoalveolar lavage and granulocytemacrophage colony-stimulating factor (GM-CSF) inhalation therapy despite having no serum anti-GM-CSF autoantibodies. At age 42, her respiratory condition became critical and she underwent transplantation from two donors. While careful observation was needed for the recurrence of PAP in the transplanted lungs, she was functioning well without oxygen therapy 1 year after transplantation. This appears to be the first report of LDLLT for PAP in an adult.

Original language	English
Pages (from-to)	1142-1144
Number of pages	3
Journal	Surgery Today
Volume	41
Issue number	8
DOIs	https://doi.org/10.1007/s00595-010-4411-0
State	Published - 2011/08

Keywords

Living-donor lobar lung transplantation
Pulmonary alveolar proteinosis

ASJC Scopus subject areas

Surgery

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10.1007/s00595-010-4411-0

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title = "Living-donor lobar lung transplantation for pulmonary alveolar proteinosis in an adult: Report of a case",

abstract = "A 43-year-old woman with pulmonary alveolar proteinosis (PAP) was successfully treated with livingdonor lobar lung transplantation (LDLLT). The patient's PAP had been diagnosed at age 35. She had been treated with repeated bronchoalveolar lavage and granulocytemacrophage colony-stimulating factor (GM-CSF) inhalation therapy despite having no serum anti-GM-CSF autoantibodies. At age 42, her respiratory condition became critical and she underwent transplantation from two donors. While careful observation was needed for the recurrence of PAP in the transplanted lungs, she was functioning well without oxygen therapy 1 year after transplantation. This appears to be the first report of LDLLT for PAP in an adult.",

keywords = "Living-donor lobar lung transplantation, Pulmonary alveolar proteinosis",

author = "Tsutomu Tagawa and Naoya Yamasaki and Tomoshi Tsuchiya and Takuro Miyazaki and Kei Matsuki and Yoshiko Tsuchihashi and Konosuke Morimoto and Takeshi Nagayasu",

year = "2011",

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doi = "10.1007/s00595-010-4411-0",

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T1 - Living-donor lobar lung transplantation for pulmonary alveolar proteinosis in an adult

T2 - Report of a case

AU - Tagawa, Tsutomu

AU - Yamasaki, Naoya

AU - Tsuchiya, Tomoshi

AU - Miyazaki, Takuro

AU - Matsuki, Kei

AU - Tsuchihashi, Yoshiko

AU - Morimoto, Konosuke

AU - Nagayasu, Takeshi

PY - 2011/8

Y1 - 2011/8

N2 - A 43-year-old woman with pulmonary alveolar proteinosis (PAP) was successfully treated with livingdonor lobar lung transplantation (LDLLT). The patient's PAP had been diagnosed at age 35. She had been treated with repeated bronchoalveolar lavage and granulocytemacrophage colony-stimulating factor (GM-CSF) inhalation therapy despite having no serum anti-GM-CSF autoantibodies. At age 42, her respiratory condition became critical and she underwent transplantation from two donors. While careful observation was needed for the recurrence of PAP in the transplanted lungs, she was functioning well without oxygen therapy 1 year after transplantation. This appears to be the first report of LDLLT for PAP in an adult.

AB - A 43-year-old woman with pulmonary alveolar proteinosis (PAP) was successfully treated with livingdonor lobar lung transplantation (LDLLT). The patient's PAP had been diagnosed at age 35. She had been treated with repeated bronchoalveolar lavage and granulocytemacrophage colony-stimulating factor (GM-CSF) inhalation therapy despite having no serum anti-GM-CSF autoantibodies. At age 42, her respiratory condition became critical and she underwent transplantation from two donors. While careful observation was needed for the recurrence of PAP in the transplanted lungs, she was functioning well without oxygen therapy 1 year after transplantation. This appears to be the first report of LDLLT for PAP in an adult.

KW - Living-donor lobar lung transplantation

KW - Pulmonary alveolar proteinosis

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Living-donor lobar lung transplantation for pulmonary alveolar proteinosis in an adult: Report of a case

Abstract

Keywords

ASJC Scopus subject areas

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