Kinetic resolution of (±)-cyclohex-1-enylsilanols by the sharpless asymmetric epoxidation

Keiji Yamamoto*, Yukio Kawanami, Masahiro Miyazawa

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

49 Scopus citations

Abstract

Unprecedented kinetic resolution of (±)-cyclohex-1-enylsilanols 1 by the Sharpless asymmetric epoxidation has been accomplished, the rate difference between enantiomers, krel, being >11 to give enantiomerically pure cyclohex-1-enylcyclohexylmethylsilanol 1b in a particular case.

Original languageEnglish
Pages (from-to)436-437
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number5
DOIs
StatePublished - 1993

ASJC Scopus subject areas

  • Molecular Medicine

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