IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress

Alana G. Lerner, John Paul Upton, P. V.K. Praveen, Rajarshi Ghosh, Yoshimi Nakagawa, Aeid Igbaria, Sarah Shen, Vinh Nguyen, Bradley J. Backes, Myriam Heiman, Nathaniel Heintz, Paul Greengard, Simon Hui, Qizhi Tang, Ala Trusina, Scott A. Oakes*, Feroz R. Papa

*Corresponding author for this work

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Keyphrases

Biochemistry, Genetics and Molecular Biology

Immunology and Microbiology