TY - JOUR
T1 - Ion-Selective Electrodes Based on Natural Carboxylic Polyether Antibiotics
AU - Suzuki, Koii
AU - Tohda, Koji
AU - Aruga, Hiroshi
AU - Matsuzoe, Misako
AU - Inoue, Hidenari
AU - Shirai, Tsuneo
PY - 1988/9/1
Y1 - 1988/9/1
N2 - The response characteristics of poly (vinyl chloride) (PVC) matrix membrane ion-selective electrodes based on five natural carboxylic polyether antibiotics, ionomycin, lasalocid, monensin, nigericin, and salinomycin, were examined. These are characterized by a good response to divalent (alkaline-earth-metal) cations such as Ca2+and Ba2+. However, electrodes based on methyl esters, in which the carboxyl groups of the natural carboxylic polyethers are esterlfled, responded weakly to divalent cations. This Indicated that the carboxyl group plays an important role In making a complex with the divalent cation in a lipophilic polymeric electrode membrane, which is significant for the electrode response to the divalent cation. Electrodes based on all the carboxylic polyethers except lasalocid show “bl-Nernstlan response” for divalent cations. In order to explain this unusual response, Ion extraction and permeability measurements were carried out with lasalocid and monensin. The general relationship between electrode response and ion extraction or ion-ligand complexation Is also discussed on the basis of the results obtained with lasalocid and monensin.
AB - The response characteristics of poly (vinyl chloride) (PVC) matrix membrane ion-selective electrodes based on five natural carboxylic polyether antibiotics, ionomycin, lasalocid, monensin, nigericin, and salinomycin, were examined. These are characterized by a good response to divalent (alkaline-earth-metal) cations such as Ca2+and Ba2+. However, electrodes based on methyl esters, in which the carboxyl groups of the natural carboxylic polyethers are esterlfled, responded weakly to divalent cations. This Indicated that the carboxyl group plays an important role In making a complex with the divalent cation in a lipophilic polymeric electrode membrane, which is significant for the electrode response to the divalent cation. Electrodes based on all the carboxylic polyethers except lasalocid show “bl-Nernstlan response” for divalent cations. In order to explain this unusual response, Ion extraction and permeability measurements were carried out with lasalocid and monensin. The general relationship between electrode response and ion extraction or ion-ligand complexation Is also discussed on the basis of the results obtained with lasalocid and monensin.
UR - http://www.scopus.com/inward/record.url?scp=0023762572&partnerID=8YFLogxK
U2 - 10.1021/ac00168a016
DO - 10.1021/ac00168a016
M3 - 学術論文
C2 - 3232811
AN - SCOPUS:0023762572
SN - 0003-2700
VL - 60
SP - 1714
EP - 1721
JO - Analytical Chemistry
JF - Analytical Chemistry
IS - 17
ER -