Integrated bio-switches: Novel biosensing devices highly suitable to actuators

M. Suzuki, S. Ito, K. Yamamoto, Y. Iribe

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Enzyme switch is a novel biosensing device based on the conductometric measurements of polyaniline film covered with oxidase enzyme and peroxidase. In this study, basic characteristics of enzyme switches were investigated. Furthermore, immunochemical switch for human serum albumin (HSA) determination was developed based on an indirect competitive enzyme immunoassay and enzyme switch principle. HSA was determined successfully by using this sensing device. Since enzyme switch is based on the electro-conductivity change, it can be inserted into electric circuits as a variable resistor. Enzyme switch was connected via simple electric circuit to actuators (pumps etc.), and the actuators could be directly controlled by enzyme switch without the use of AD/DA converters and PCs. Finally 9 channel 3-D paired electrodes were prepared and 9 enzyme switches were integrated on one chip. The response characteristics of this integrated enzyme switch were investigated.

Original languageEnglish
Title of host publicationTRANSDUCERS 2003 - 12th International Conference on Solid-State Sensors, Actuators and Microsystems, Digest of Technical Papers
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1205-1208
Number of pages4
ISBN (Electronic)0780377311, 9780780377318
DOIs
StatePublished - 2003
Event12th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2003 - Digest of Technical Papers - Boston, United States
Duration: 2003/06/082003/06/12

Publication series

NameTRANSDUCERS 2003 - 12th International Conference on Solid-State Sensors, Actuators and Microsystems, Digest of Technical Papers
Volume2

Conference

Conference12th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2003 - Digest of Technical Papers
Country/TerritoryUnited States
CityBoston
Period2003/06/082003/06/12

Keywords

  • Actuators
  • Biochemistry
  • Biosensors
  • Conductive films
  • Electric variables control
  • Humans
  • Immune system
  • Resistors
  • Switches
  • Switching circuits

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

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