Insular cortex volume in established bipolar affective disorder: A preliminary MRI study

Tsutomu Takahashi*, Gin S. Malhi, Stephen J. Wood, Murat Yücel, Mark Walterfang, Ryoichiro Tanino, Michio Suzuki, Christos Pantelis

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

This structural magnetic resonance imaging study investigated insular cortex volume in 26 patients with bipolar I disorder and 24 matched controls. While insular volume did not differ between these groups, exploratory analyses demonstrated that the number of depressive episodes correlated negatively with the anterior insular volume in the patients, suggesting it may have a role in the pathophysiology of bipolar disorder.

Original languageEnglish
Pages (from-to)187-190
Number of pages4
JournalPsychiatry Research - Neuroimaging
Volume182
Issue number2
DOIs
StatePublished - 2010/05

Keywords

  • Bipolar I disorder
  • Insula
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Psychiatry and Mental health

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