In Situ Formation of a Relatively Transparent Ion-Associate Liquid Phase from an Aqueous Phase and Its Application to Microextraction/High-Performance Liquid Chromatography-Fluorescence Detection of Bisphenol A in Water

Noriko Hata; Seira Takahashi; Sachiko Osada; Sakura Katagiri; Mayumi Naruse; Akane Igarashi; Kazuto Sazawa; Shigeru Taguchi; Hideki Kuramitz

doi:10.3390/molecules28227525

In Situ Formation of a Relatively Transparent Ion-Associate Liquid Phase from an Aqueous Phase and Its Application to Microextraction/High-Performance Liquid Chromatography-Fluorescence Detection of Bisphenol A in Water

Noriko Hata, Seira Takahashi, Sachiko Osada, Sakura Katagiri, Mayumi Naruse, Akane Igarashi, Kazuto Sazawa, Shigeru Taguchi, Hideki Kuramitz

University of Toyama

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The design of a simple approach enabling the detection of bisphenol A (BPA) in water samples without the need for large amounts of solvents is of utmost importance. This paper reports a simple method for the separation, concentration, and quantification of BPA in water samples using high-performance liquid chromatography with fluorescence detection (HPLC-FLD) after its microextraction into an in situ formed organic ion-associate (IA) liquid phase (LP). Novel IA phase components without conjugated double bonds, such as benzene rings, were investigated. Ethylhexyloxypropylamine hydrochloride and sodium dodecyl sulfate solutions were added to the water samples to form IAs. The aqueous phase and ion-associate liquid phase (IALP) were separated by centrifugation. The aqueous phase was removed, and the liquid phase was recovered and measured using HPLC-FLD or HPLC-electrochemical detection (ECD). The concentrated phase (IALP) had a relatively low viscosity and could be injected directly into the chromatograph without dissolving it in organic solvents. The detection limits for BPA by HPLC-FLD and HPLC-ECD were 0.009 and 0.3 µg L-1, respectively.

Original language	English
Journal	Molecules
Volume	28
Issue number	22
DOIs	https://doi.org/10.3390/molecules28227525
State	Published - 2023/11/10

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Hata, N., Takahashi, S., Osada, S., Katagiri, S., Naruse, M., Igarashi, A., Sazawa, K., Taguchi, S., & Kuramitz, H. (2023). In Situ Formation of a Relatively Transparent Ion-Associate Liquid Phase from an Aqueous Phase and Its Application to Microextraction/High-Performance Liquid Chromatography-Fluorescence Detection of Bisphenol A in Water. Molecules, 28(22). https://doi.org/10.3390/molecules28227525

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title = "In Situ Formation of a Relatively Transparent Ion-Associate Liquid Phase from an Aqueous Phase and Its Application to Microextraction/High-Performance Liquid Chromatography-Fluorescence Detection of Bisphenol A in Water",

abstract = "The design of a simple approach enabling the detection of bisphenol A (BPA) in water samples without the need for large amounts of solvents is of utmost importance. This paper reports a simple method for the separation, concentration, and quantification of BPA in water samples using high-performance liquid chromatography with fluorescence detection (HPLC-FLD) after its microextraction into an in situ formed organic ion-associate (IA) liquid phase (LP). Novel IA phase components without conjugated double bonds, such as benzene rings, were investigated. Ethylhexyloxypropylamine hydrochloride and sodium dodecyl sulfate solutions were added to the water samples to form IAs. The aqueous phase and ion-associate liquid phase (IALP) were separated by centrifugation. The aqueous phase was removed, and the liquid phase was recovered and measured using HPLC-FLD or HPLC-electrochemical detection (ECD). The concentrated phase (IALP) had a relatively low viscosity and could be injected directly into the chromatograph without dissolving it in organic solvents. The detection limits for BPA by HPLC-FLD and HPLC-ECD were 0.009 and 0.3 µg L-1, respectively.",

author = "Noriko Hata and Seira Takahashi and Sachiko Osada and Sakura Katagiri and Mayumi Naruse and Akane Igarashi and Kazuto Sazawa and Shigeru Taguchi and Hideki Kuramitz",

year = "2023",

month = nov,

day = "10",

doi = "10.3390/molecules28227525",

language = "英語",

volume = "28",

journal = "Molecules",

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Hata, N, Takahashi, S, Osada, S, Katagiri, S, Naruse, M, Igarashi, A, Sazawa, K, Taguchi, S & Kuramitz, H 2023, 'In Situ Formation of a Relatively Transparent Ion-Associate Liquid Phase from an Aqueous Phase and Its Application to Microextraction/High-Performance Liquid Chromatography-Fluorescence Detection of Bisphenol A in Water', Molecules, vol. 28, no. 22. https://doi.org/10.3390/molecules28227525

In Situ Formation of a Relatively Transparent Ion-Associate Liquid Phase from an Aqueous Phase and Its Application to Microextraction/High-Performance Liquid Chromatography-Fluorescence Detection of Bisphenol A in Water. / Hata, Noriko; Takahashi, Seira; Osada, Sachiko et al.
In: Molecules, Vol. 28, No. 22, 10.11.2023.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - In Situ Formation of a Relatively Transparent Ion-Associate Liquid Phase from an Aqueous Phase and Its Application to Microextraction/High-Performance Liquid Chromatography-Fluorescence Detection of Bisphenol A in Water

AU - Hata, Noriko

AU - Takahashi, Seira

AU - Osada, Sachiko

AU - Katagiri, Sakura

AU - Naruse, Mayumi

AU - Igarashi, Akane

AU - Sazawa, Kazuto

AU - Taguchi, Shigeru

AU - Kuramitz, Hideki

PY - 2023/11/10

Y1 - 2023/11/10

N2 - The design of a simple approach enabling the detection of bisphenol A (BPA) in water samples without the need for large amounts of solvents is of utmost importance. This paper reports a simple method for the separation, concentration, and quantification of BPA in water samples using high-performance liquid chromatography with fluorescence detection (HPLC-FLD) after its microextraction into an in situ formed organic ion-associate (IA) liquid phase (LP). Novel IA phase components without conjugated double bonds, such as benzene rings, were investigated. Ethylhexyloxypropylamine hydrochloride and sodium dodecyl sulfate solutions were added to the water samples to form IAs. The aqueous phase and ion-associate liquid phase (IALP) were separated by centrifugation. The aqueous phase was removed, and the liquid phase was recovered and measured using HPLC-FLD or HPLC-electrochemical detection (ECD). The concentrated phase (IALP) had a relatively low viscosity and could be injected directly into the chromatograph without dissolving it in organic solvents. The detection limits for BPA by HPLC-FLD and HPLC-ECD were 0.009 and 0.3 µg L-1, respectively.

AB - The design of a simple approach enabling the detection of bisphenol A (BPA) in water samples without the need for large amounts of solvents is of utmost importance. This paper reports a simple method for the separation, concentration, and quantification of BPA in water samples using high-performance liquid chromatography with fluorescence detection (HPLC-FLD) after its microextraction into an in situ formed organic ion-associate (IA) liquid phase (LP). Novel IA phase components without conjugated double bonds, such as benzene rings, were investigated. Ethylhexyloxypropylamine hydrochloride and sodium dodecyl sulfate solutions were added to the water samples to form IAs. The aqueous phase and ion-associate liquid phase (IALP) were separated by centrifugation. The aqueous phase was removed, and the liquid phase was recovered and measured using HPLC-FLD or HPLC-electrochemical detection (ECD). The concentrated phase (IALP) had a relatively low viscosity and could be injected directly into the chromatograph without dissolving it in organic solvents. The detection limits for BPA by HPLC-FLD and HPLC-ECD were 0.009 and 0.3 µg L-1, respectively.

U2 - 10.3390/molecules28227525

DO - 10.3390/molecules28227525

M3 - 学術論文

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SN - 1420-3049

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JO - Molecules

JF - Molecules

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ER -