Impact of Mannitol Administration on Postoperative Renal Function After Robot-Assisted Partial Nephrectomy

Kazuki Taniguchi; Tomoki Taniguchi; Kentaro Muraoka; Kohei Nishikawa; Yoshinori Ikehata; Kiyoshi Setoguchi; Suguru Oka; Shin Ebara; Akira Fujisaki; Kazuhide Makiyama; Takahiro Inoue; Hiroshi Kitamura; Kazutaka Saito; Shinji Urakami; Tatsuaki Yoneda; Takuya Koie

doi:10.3390/jcm13216444

Impact of Mannitol Administration on Postoperative Renal Function After Robot-Assisted Partial Nephrectomy

Kazuki Taniguchi, Tomoki Taniguchi^*, Kentaro Muraoka, Kohei Nishikawa, Yoshinori Ikehata, Kiyoshi Setoguchi, Suguru Oka, Shin Ebara, Akira Fujisaki, Kazuhide Makiyama, Takahiro Inoue, Hiroshi Kitamura, Kazutaka Saito, Shinji Urakami, Tatsuaki Yoneda, Takuya Koie

^*Corresponding author for this work

Urology

Research output: Contribution to journal › Article › peer-review

Abstract

Background: This study investigated the effect of mannitol administration on postoperative renal function during robot-assisted partial nephrectomy (RAPN) in patients with renal cell carcinoma (RCC). Methods: Patients with RCC who underwent RAPN at eight Japanese facilities between March 2016 and November 2023 were enrolled. In this study, patients were categorized into two groups according to those who received mannitol during RAPN (Group I) and those who did not receive mannitol (Group II). Differences in covariates between the two groups were adjusted using propensity score matching (PSM). Results: The study included 1530 patients with RCC who underwent RAPN. PSM was performed on 531 participants in each group. No difference was observed in perioperative outcomes between the two groups in terms of length of hospital stay, surgical outcomes, achievement ratio of Trifecta, and estimated glomerular filtration rate at 28 days, 90 days, and 1 year postoperatively. Conclusions: Intraoperative mannitol administration during RAPN for improving renal function may be unnecessary.

Original language	English
Article number	6444
Journal	Journal of Clinical Medicine
Volume	13
Issue number	21
DOIs	https://doi.org/10.3390/jcm13216444
State	Published - 2024/11

Keywords

mannitol
postoperative renal function
renal cell carcinoma
robot-assisted partial nephrectomy

ASJC Scopus subject areas

General Medicine

Access to Document

10.3390/jcm13216444

Cite this

Taniguchi, K., Taniguchi, T., Muraoka, K., Nishikawa, K., Ikehata, Y., Setoguchi, K., Oka, S., Ebara, S., Fujisaki, A., Makiyama, K., Inoue, T., Kitamura, H., Saito, K., Urakami, S., Yoneda, T., & Koie, T. (2024). Impact of Mannitol Administration on Postoperative Renal Function After Robot-Assisted Partial Nephrectomy. Journal of Clinical Medicine, 13(21), Article 6444. https://doi.org/10.3390/jcm13216444

@article{88e83b548b974073995d4d54af858ee6,

title = "Impact of Mannitol Administration on Postoperative Renal Function After Robot-Assisted Partial Nephrectomy",

abstract = "Background: This study investigated the effect of mannitol administration on postoperative renal function during robot-assisted partial nephrectomy (RAPN) in patients with renal cell carcinoma (RCC). Methods: Patients with RCC who underwent RAPN at eight Japanese facilities between March 2016 and November 2023 were enrolled. In this study, patients were categorized into two groups according to those who received mannitol during RAPN (Group I) and those who did not receive mannitol (Group II). Differences in covariates between the two groups were adjusted using propensity score matching (PSM). Results: The study included 1530 patients with RCC who underwent RAPN. PSM was performed on 531 participants in each group. No difference was observed in perioperative outcomes between the two groups in terms of length of hospital stay, surgical outcomes, achievement ratio of Trifecta, and estimated glomerular filtration rate at 28 days, 90 days, and 1 year postoperatively. Conclusions: Intraoperative mannitol administration during RAPN for improving renal function may be unnecessary.",

keywords = "mannitol, postoperative renal function, renal cell carcinoma, robot-assisted partial nephrectomy",

author = "Kazuki Taniguchi and Tomoki Taniguchi and Kentaro Muraoka and Kohei Nishikawa and Yoshinori Ikehata and Kiyoshi Setoguchi and Suguru Oka and Shin Ebara and Akira Fujisaki and Kazuhide Makiyama and Takahiro Inoue and Hiroshi Kitamura and Kazutaka Saito and Shinji Urakami and Tatsuaki Yoneda and Takuya Koie",

note = "Publisher Copyright: {\textcopyright} 2024 by the authors.",

year = "2024",

month = nov,

doi = "10.3390/jcm13216444",

language = "英語",

volume = "13",

journal = "Journal of Clinical Medicine",

issn = "2077-0383",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "21",

}

Taniguchi, K, Taniguchi, T, Muraoka, K, Nishikawa, K, Ikehata, Y, Setoguchi, K, Oka, S, Ebara, S, Fujisaki, A, Makiyama, K, Inoue, T, Kitamura, H, Saito, K, Urakami, S, Yoneda, T & Koie, T 2024, 'Impact of Mannitol Administration on Postoperative Renal Function After Robot-Assisted Partial Nephrectomy', Journal of Clinical Medicine, vol. 13, no. 21, 6444. https://doi.org/10.3390/jcm13216444

TY - JOUR

T1 - Impact of Mannitol Administration on Postoperative Renal Function After Robot-Assisted Partial Nephrectomy

AU - Taniguchi, Kazuki

AU - Taniguchi, Tomoki

AU - Muraoka, Kentaro

AU - Nishikawa, Kohei

AU - Ikehata, Yoshinori

AU - Setoguchi, Kiyoshi

AU - Oka, Suguru

AU - Ebara, Shin

AU - Fujisaki, Akira

AU - Makiyama, Kazuhide

AU - Inoue, Takahiro

AU - Kitamura, Hiroshi

AU - Saito, Kazutaka

AU - Urakami, Shinji

AU - Yoneda, Tatsuaki

AU - Koie, Takuya

PY - 2024/11

Y1 - 2024/11

N2 - Background: This study investigated the effect of mannitol administration on postoperative renal function during robot-assisted partial nephrectomy (RAPN) in patients with renal cell carcinoma (RCC). Methods: Patients with RCC who underwent RAPN at eight Japanese facilities between March 2016 and November 2023 were enrolled. In this study, patients were categorized into two groups according to those who received mannitol during RAPN (Group I) and those who did not receive mannitol (Group II). Differences in covariates between the two groups were adjusted using propensity score matching (PSM). Results: The study included 1530 patients with RCC who underwent RAPN. PSM was performed on 531 participants in each group. No difference was observed in perioperative outcomes between the two groups in terms of length of hospital stay, surgical outcomes, achievement ratio of Trifecta, and estimated glomerular filtration rate at 28 days, 90 days, and 1 year postoperatively. Conclusions: Intraoperative mannitol administration during RAPN for improving renal function may be unnecessary.

AB - Background: This study investigated the effect of mannitol administration on postoperative renal function during robot-assisted partial nephrectomy (RAPN) in patients with renal cell carcinoma (RCC). Methods: Patients with RCC who underwent RAPN at eight Japanese facilities between March 2016 and November 2023 were enrolled. In this study, patients were categorized into two groups according to those who received mannitol during RAPN (Group I) and those who did not receive mannitol (Group II). Differences in covariates between the two groups were adjusted using propensity score matching (PSM). Results: The study included 1530 patients with RCC who underwent RAPN. PSM was performed on 531 participants in each group. No difference was observed in perioperative outcomes between the two groups in terms of length of hospital stay, surgical outcomes, achievement ratio of Trifecta, and estimated glomerular filtration rate at 28 days, 90 days, and 1 year postoperatively. Conclusions: Intraoperative mannitol administration during RAPN for improving renal function may be unnecessary.

KW - mannitol

KW - postoperative renal function

KW - renal cell carcinoma

KW - robot-assisted partial nephrectomy

UR - http://www.scopus.com/inward/record.url?scp=85208593014&partnerID=8YFLogxK

U2 - 10.3390/jcm13216444

DO - 10.3390/jcm13216444

M3 - 学術論文

C2 - 39518583

AN - SCOPUS:85208593014

SN - 2077-0383

VL - 13

JO - Journal of Clinical Medicine

JF - Journal of Clinical Medicine

IS - 21

M1 - 6444

ER -

Impact of Mannitol Administration on Postoperative Renal Function After Robot-Assisted Partial Nephrectomy

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Fingerprint

Cite this