Hypopituitarism caused by hypothalamic metastasis of lung cancer

Hirokazu Taniguchi*, Minehiko Inomata, Hitoshi Abo, Hideki Miyazawa, Hirofumi Noto, Saburo Izumi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A 40-year-old man was admitted due to thirst, general malaise, and swollen cervical lymph nodes. Cervical lymph node biopsy revealed moderately differentiated adenocarcinoma, and he was diagnosed lung cancer with hypothalamic metastasis. We gave him chemotherapy and hypothalamic irradiation. He had mild hydrodipsia at the first examination, which progressively worsened. He was given a diagnosis of diabetes insipidus caused by hypothalamic metastasis. We gave him desmopressin acetate, and his symptom improved. Predonisolone was prescribed, because of low levels of adrenocorticotropic hormone in the blood. After chemotherapy and irradiation of hypothalamus, metastatic focus diminished and desmopressin acetate was tapered. Hypopituitarism caused by hypothalamic metastasis is rare.

Original languageEnglish
Pages (from-to)1030-1033
Number of pages4
JournalNihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
Volume42
Issue number12
StatePublished - 2004/12

ASJC Scopus subject areas

  • General Medicine

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