Hypervalent Iodine Oxidation of Ethynylcarbinols: A Short and Efficient Conversion of Dihydroxy-acetonyl Groups from Keto Groups

Yasuyuki Kita; Takayuki Yakura; Hiroaki Terashi; Jun ichi Haruta; Yasumitsu Tamura

doi:10.1248/cpb.37.891

Hypervalent Iodine Oxidation of Ethynylcarbinols: A Short and Efficient Conversion of Dihydroxy-acetonyl Groups from Keto Groups

Yasuyuki Kita, Takayuki Yakura, Hiroaki Terashi, Jun ichi Haruta, Yasumitsu Tamura

Synthetic and Biomolecular Organic Chemistry

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Oxidation of ethynylcarbinols (4a—g), prepared easily from ketones, with a hypervalent iodine reagent, phenyliodosyl bis(trifluoroacetate) (PIFA), in chloroform-acetonitrile-water gave the dihydroxyacetonyl compounds (6a—g) in high yields.

Original language	English
Pages (from-to)	891-894
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	37
Issue number	4
DOIs	https://doi.org/10.1248/cpb.37.891
State	Published - 1989

Keywords

a-hydroxyketone
dihydroxyacetone
ethynylcarbinol
phenyliodosyl bis(trifluoroacetate)
terminal alkyne

ASJC Scopus subject areas

General Chemistry
Drug Discovery

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10.1248/cpb.37.891

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abstract = "Oxidation of ethynylcarbinols (4a—g), prepared easily from ketones, with a hypervalent iodine reagent, phenyliodosyl bis(trifluoroacetate) (PIFA), in chloroform-acetonitrile-water gave the dihydroxyacetonyl compounds (6a—g) in high yields.",

keywords = "a-hydroxyketone, dihydroxyacetone, ethynylcarbinol, phenyliodosyl bis(trifluoroacetate), terminal alkyne",

author = "Yasuyuki Kita and Takayuki Yakura and Hiroaki Terashi and Haruta, {Jun ichi} and Yasumitsu Tamura",

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doi = "10.1248/cpb.37.891",

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T2 - A Short and Efficient Conversion of Dihydroxy-acetonyl Groups from Keto Groups

AU - Kita, Yasuyuki

AU - Yakura, Takayuki

AU - Terashi, Hiroaki

AU - Haruta, Jun ichi

AU - Tamura, Yasumitsu

PY - 1989

Y1 - 1989

N2 - Oxidation of ethynylcarbinols (4a—g), prepared easily from ketones, with a hypervalent iodine reagent, phenyliodosyl bis(trifluoroacetate) (PIFA), in chloroform-acetonitrile-water gave the dihydroxyacetonyl compounds (6a—g) in high yields.

AB - Oxidation of ethynylcarbinols (4a—g), prepared easily from ketones, with a hypervalent iodine reagent, phenyliodosyl bis(trifluoroacetate) (PIFA), in chloroform-acetonitrile-water gave the dihydroxyacetonyl compounds (6a—g) in high yields.

KW - a-hydroxyketone

KW - dihydroxyacetone

KW - ethynylcarbinol

KW - phenyliodosyl bis(trifluoroacetate)

KW - terminal alkyne

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U2 - 10.1248/cpb.37.891

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M3 - 学術論文

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IS - 4

ER -

Hypervalent Iodine Oxidation of Ethynylcarbinols: A Short and Efficient Conversion of Dihydroxy-acetonyl Groups from Keto Groups

Abstract

Keywords

ASJC Scopus subject areas

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