Abstract
Oxidation of non-enolizable α,β-unsaturated carbonyl compounds and enolizable β-monosubstituted α,β-unsaturated carbonyl compounds with phenyl iodine(III) diacetate (PIDA) in methanolic potassium hydroxide gave α-hydroxydimethylacetal β-methoxy products, and oxidation of enolizable β,β-disubstituted α,β-unsaturated carbonyl compounds under the same conditions gave α’-hydroxy products.
| Original language | English |
|---|---|
| Pages (from-to) | 570-577 |
| Number of pages | 8 |
| Journal | Chemical and Pharmaceutical Bulletin |
| Volume | 35 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1987 |
Keywords
- methanolic potassium hydroxide solution
- oxidation of α,β-unsaturated carbonyl compound
- phenyl iodine(III) diacetate
- α-hydroxydimethylacetal β-methoxy product
- α’-hydroxy-α,β-unsaturated ketone
ASJC Scopus subject areas
- General Chemistry
- Drug Discovery