@article{1bc1d7d012944242b9206a4fa7d3c6dc,
title = "Genetic association study of KREMEN1 and DKK1 and schizophrenia in a Japanese population",
abstract = "The aim of the current study was to examine the association of KREMEN1 and DKK1, two wnt pathway-related genes with schizophrenia in Japanese subjects. We genotyped 16 common genetic variants within the aforementioned genes and examined their associations with schizophrenia. Results demonstrated that a common variant in the promoter region of KREMEN1 might modulate the risk of schizophrenia in the Japanese. However, further replication will be needed for conclusive interpretation of the effect of this locus on the pathogenesis of schizophrenia.",
keywords = "DKK1, Epistasis, Japanese population, KREMEN1, Schizophrenia, Wnt pathway",
author = "Branko Aleksic and Itaru Kushima and Yoshihito Ito and Yukako Nakamura and Hiroshi Ujike and Michio Suzuki and Toshiya Inada and Ryota Hashimoto and Masatoshi Takeda and Nakao Iwata and Norio Ozaki",
note = "Funding Information: Funding for this study was provided by research grants from the Ministry of Education, Culture, Sports, Science and Technology of Japan; the Ministry of Health, Labor and Welfare of Japan; Grant-in-Aid for Scientific Research on Pathomechanisms of Brain Disorders from the Ministry of Education, Culture, Sports, Science and Technology of Japan; The Academic Frontier Project for Private Universities, Comparative Cognitive Science Institutes; and the Core Research for Evolutional Science and Technology. These institutions had no further role in the study design; the collection, analysis, and interpretation of the data; the writing of this report; or the decision to submit the paper for publication. ",
year = "2010",
month = may,
doi = "10.1016/j.schres.2010.01.014",
language = "英語",
volume = "118",
pages = "113--117",
journal = "Schizophrenia Research",
issn = "0920-9964",
publisher = "Elsevier B.V.",
number = "1-3",
}
