Expeditious and stereoselective synthesis of chiral trans -β-hydroxy-δ-lactone systems

Masahiro Miyazawa; Erika Matsuoka; Shinobu Sasaki; Satoshi Oonuma; Kimiyuki Maruyama; Masaaki Miyashita

doi:10.1246/cl.1998.109

Expeditious and stereoselective synthesis of chiral trans -β-hydroxy-δ-lactone systems

Masahiro Miyazawa, Erika Matsuoka, Shinobu Sasaki, Satoshi Oonuma, Kimiyuki Maruyama, Masaaki Miyashita^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Expeditious and stereoselective synthesis of chiral trans-β-hydroxy-δ-lactone systems starting from γ,δ-epoxy acrylates is described which involves the regioselective ring opening of an epoxide and the intramolecular conjugate addition of a hemiacetal alkoxide anion of δ-hydroxy-α,β-unsaturated esters as key steps.

Original language	English
Pages (from-to)	109-110
Number of pages	2
Journal	Chemistry Letters
Issue number	2
DOIs	https://doi.org/10.1246/cl.1998.109
State	Published - 1998

ASJC Scopus subject areas

General Chemistry

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10.1246/cl.1998.109

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title = "Expeditious and stereoselective synthesis of chiral trans -β-hydroxy-δ-lactone systems",

abstract = "Expeditious and stereoselective synthesis of chiral trans-β-hydroxy-δ-lactone systems starting from γ,δ-epoxy acrylates is described which involves the regioselective ring opening of an epoxide and the intramolecular conjugate addition of a hemiacetal alkoxide anion of δ-hydroxy-α,β-unsaturated esters as key steps.",

author = "Masahiro Miyazawa and Erika Matsuoka and Shinobu Sasaki and Satoshi Oonuma and Kimiyuki Maruyama and Masaaki Miyashita",

year = "1998",

doi = "10.1246/cl.1998.109",

language = "英語",

pages = "109--110",

journal = "Chemistry Letters",

issn = "0366-7022",

publisher = "Oxford University Press",

number = "2",

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TY - JOUR

T1 - Expeditious and stereoselective synthesis of chiral trans -β-hydroxy-δ-lactone systems

AU - Miyazawa, Masahiro

AU - Matsuoka, Erika

AU - Sasaki, Shinobu

AU - Oonuma, Satoshi

AU - Maruyama, Kimiyuki

AU - Miyashita, Masaaki

PY - 1998

Y1 - 1998

N2 - Expeditious and stereoselective synthesis of chiral trans-β-hydroxy-δ-lactone systems starting from γ,δ-epoxy acrylates is described which involves the regioselective ring opening of an epoxide and the intramolecular conjugate addition of a hemiacetal alkoxide anion of δ-hydroxy-α,β-unsaturated esters as key steps.

AB - Expeditious and stereoselective synthesis of chiral trans-β-hydroxy-δ-lactone systems starting from γ,δ-epoxy acrylates is described which involves the regioselective ring opening of an epoxide and the intramolecular conjugate addition of a hemiacetal alkoxide anion of δ-hydroxy-α,β-unsaturated esters as key steps.

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U2 - 10.1246/cl.1998.109

DO - 10.1246/cl.1998.109

M3 - 学術論文

AN - SCOPUS:0001290552

SN - 0366-7022

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EP - 110

JO - Chemistry Letters

JF - Chemistry Letters

IS - 2

ER -

Expeditious and stereoselective synthesis of chiral trans -β-hydroxy-δ-lactone systems

Abstract

ASJC Scopus subject areas

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