DNA cleavage based on high voltage electric pulse

Eiichi Tamiya*, Yoshiko Nakajima, Hiroyuki Kamioka, Masayasu Suzuki, Isao Karube

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

A high voltage electric pulse was applied to DNA cleavage. The DNA cleavage reaction was dependent on the voltage amplitude, pulse number and pulse width. Radical scavengers and ESR data indicated the possibility that active species such as OH radical were strongly related to DNA cleavage.

Original languageEnglish
Pages (from-to)357-361
Number of pages5
JournalFEBS Letters
Volume234
Issue number2
DOIs
StatePublished - 1988/07/18

Keywords

  • DNA cleavage
  • ESR
  • Electric pulse
  • Electrochemistry
  • Oxygen radical
  • Radical scavenger

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

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