Diffuse alveolar damage after inhalation of zinc oxide fumes

Hirokazu Taniguchi; Kensuke Suzuki; Shiho Fujisaka; Rieko Honda; Hitoshi Abo; Hideki Miyazawa; Hirofumi Noto; Saburo Izumi

Diffuse alveolar damage after inhalation of zinc oxide fumes

Hirokazu Taniguchi^*, Kensuke Suzuki, Shiho Fujisaka, Rieko Honda, Hitoshi Abo, Hideki Miyazawa, Hirofumi Noto, Saburo Izumi

^*Corresponding author for this work

Internal Medicine （1）

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A 57-year-old man with a 37-year occupational history of welding was admitted for high fever and dyspnea after inhalation of zinc oxide fumes during a period of welding without a protective mask. Chest radiography and CT showed bilateral diffuse ground-glass opacities, and blood gas analysis revealed that PaO2 was 48.1 torr in room air. A transbronchial lung biopsy was done, and revealed diffuse alveolar damage. We diagnosed the case as chemical pneumonia due to the inhalation of zinc oxide, and prescribed prednisolone 40 mg per day. As a result, his symptoms improved within several days. The inhalation of zinc oxide fume usually causes metal fume fever, but chemical pneumonia is also reported on rare occasions. As far as our examination of the literature has disclosed, this is the first report of diffuse alveolar damage after inhalation of zinc oxide fume.

Original language	English
Pages (from-to)	447-450
Number of pages	4
Journal	Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
Volume	41
Issue number	7
State	Published - 2003/07

ASJC Scopus subject areas

General Medicine

Cite this

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title = "Diffuse alveolar damage after inhalation of zinc oxide fumes",

abstract = "A 57-year-old man with a 37-year occupational history of welding was admitted for high fever and dyspnea after inhalation of zinc oxide fumes during a period of welding without a protective mask. Chest radiography and CT showed bilateral diffuse ground-glass opacities, and blood gas analysis revealed that PaO2 was 48.1 torr in room air. A transbronchial lung biopsy was done, and revealed diffuse alveolar damage. We diagnosed the case as chemical pneumonia due to the inhalation of zinc oxide, and prescribed prednisolone 40 mg per day. As a result, his symptoms improved within several days. The inhalation of zinc oxide fume usually causes metal fume fever, but chemical pneumonia is also reported on rare occasions. As far as our examination of the literature has disclosed, this is the first report of diffuse alveolar damage after inhalation of zinc oxide fume.",

author = "Hirokazu Taniguchi and Kensuke Suzuki and Shiho Fujisaka and Rieko Honda and Hitoshi Abo and Hideki Miyazawa and Hirofumi Noto and Saburo Izumi",

year = "2003",

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TY - JOUR

T1 - Diffuse alveolar damage after inhalation of zinc oxide fumes

AU - Taniguchi, Hirokazu

AU - Suzuki, Kensuke

AU - Fujisaka, Shiho

AU - Honda, Rieko

AU - Abo, Hitoshi

AU - Miyazawa, Hideki

AU - Noto, Hirofumi

AU - Izumi, Saburo

PY - 2003/7

Y1 - 2003/7

N2 - A 57-year-old man with a 37-year occupational history of welding was admitted for high fever and dyspnea after inhalation of zinc oxide fumes during a period of welding without a protective mask. Chest radiography and CT showed bilateral diffuse ground-glass opacities, and blood gas analysis revealed that PaO2 was 48.1 torr in room air. A transbronchial lung biopsy was done, and revealed diffuse alveolar damage. We diagnosed the case as chemical pneumonia due to the inhalation of zinc oxide, and prescribed prednisolone 40 mg per day. As a result, his symptoms improved within several days. The inhalation of zinc oxide fume usually causes metal fume fever, but chemical pneumonia is also reported on rare occasions. As far as our examination of the literature has disclosed, this is the first report of diffuse alveolar damage after inhalation of zinc oxide fume.

AB - A 57-year-old man with a 37-year occupational history of welding was admitted for high fever and dyspnea after inhalation of zinc oxide fumes during a period of welding without a protective mask. Chest radiography and CT showed bilateral diffuse ground-glass opacities, and blood gas analysis revealed that PaO2 was 48.1 torr in room air. A transbronchial lung biopsy was done, and revealed diffuse alveolar damage. We diagnosed the case as chemical pneumonia due to the inhalation of zinc oxide, and prescribed prednisolone 40 mg per day. As a result, his symptoms improved within several days. The inhalation of zinc oxide fume usually causes metal fume fever, but chemical pneumonia is also reported on rare occasions. As far as our examination of the literature has disclosed, this is the first report of diffuse alveolar damage after inhalation of zinc oxide fume.

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M3 - 学術論文

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SN - 1343-3490

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EP - 450

JO - Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society

JF - Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society

IS - 7

ER -

Diffuse alveolar damage after inhalation of zinc oxide fumes

Abstract

ASJC Scopus subject areas

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