Deep ocean water alters the cholesterol and mineral metabolism of squid Todarodes pacificus and suppresses its weight loss

Kaito Hatano, Masa Aki Yoshida, Jun Hirayama, Yoichiro Kitani, Atsuhiko Hattori, Shouzo Ogiso, Yukina Watabe, Toshio Sekiguchi, Yoshiaki Tabuchi, Makoto Urata, Kyoko Matsumoto, Akihiro Sakatoku, Ajai K. Srivastav, Kenji Toyota, Hajime Matsubara, Nobuo Suzuki*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

This study is the first to demonstrate that deep ocean water (DOW) has physiological significant effects on squid. After 36 h of rearing squids, those reared with DOW had significantly higher total and free cholesterol levels and lower alanine transaminase activity in hemolymph as compared with those reared with surface sea water (SSW). SSW rearing also resulted in 6.95% weight loss, while DOW rearing caused only 2.5% weight loss, which might be due to liver metabolism suppression. Furthermore, both monovalent (sodium, chloride, and potassium ions) and divalent (calcium, inorganic phosphorus, and magnesium ions) ions in hemolymph were elevated when reared with DOW compared to those when reared with SSW. A study of genes expressed in the brain revealed that five genes were specifically remarked in DOW rearing. Most altered genes were neuropeptides, including those from vasopressin superfamily. These neuropeptides are involved in cholesterol and/or mineral metabolisms and physiological significant effects on squid. This study is the first report the effects of DOW on cholesterol and mineral metabolism of squid and will contribute to squid aquaculture using DOW.

Original languageEnglish
Article number7591
JournalScientific Reports
Volume13
Issue number1
DOIs
StatePublished - 2023/12

ASJC Scopus subject areas

  • General

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