Correlation between the structure of water in the vicinity of carboxybetaine polymers and their biocompatibility

Susumu Tada; Takayuki Mori; Makoto Gemmei-Ide; Hiromi Kitano; Mitsuhiro Fukuda; Masaru Tanaka

Correlation between the structure of water in the vicinity of carboxybetaine polymers and their biocompatibility

Susumu Tada^*, Takayuki Mori, Makoto Gemmei-Ide, Hiromi Kitano, Mitsuhiro Fukuda, Masaru Tanaka

^*Corresponding author for this work

Applied Chemistry

Research output: Contribution to conference › Paper › peer-review

Abstract

Structure of water in the vicinity of carboxybetaine (CMB), n-buthyl methacrylate (BMA) polymers and their copolymers with various compositions was investigated by using vibrational spectroscopies. Raman spectroscopy has revealed that, in contrast with ordinary polyelectrolytes, the zwitterionic polymers, PCMB and water-soluble P(BMA/CMB), did not affect the hydrogen-bonded network structure of water in their aqueous solutions. ATR-IR spectra of water sorbed into the P(BMA/CMB) films was similar to that of free water, but that in PBMA film was not. The number of platelets adhered to the P(BMA/CMB) films was much smaller than that into PBMA film. These results suggest that the water structure is very important factor to generate biocompatibility of polymers.

Original language	English
Pages	3826-3827
Number of pages	2
State	Published - 2005
Event	54th SPSJ Symposium on Macromolecules - Yamagata, Japan Duration: 2005/09/20 → 2005/09/22

Conference

Conference	54th SPSJ Symposium on Macromolecules
Country/Territory	Japan
City	Yamagata
Period	2005/09/20 → 2005/09/22

Keywords

Biocompatibility
Carboxybetaine polymer
Structure of water

ASJC Scopus subject areas

General Engineering

Cite this

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title = "Correlation between the structure of water in the vicinity of carboxybetaine polymers and their biocompatibility",

abstract = "Structure of water in the vicinity of carboxybetaine (CMB), n-buthyl methacrylate (BMA) polymers and their copolymers with various compositions was investigated by using vibrational spectroscopies. Raman spectroscopy has revealed that, in contrast with ordinary polyelectrolytes, the zwitterionic polymers, PCMB and water-soluble P(BMA/CMB), did not affect the hydrogen-bonded network structure of water in their aqueous solutions. ATR-IR spectra of water sorbed into the P(BMA/CMB) films was similar to that of free water, but that in PBMA film was not. The number of platelets adhered to the P(BMA/CMB) films was much smaller than that into PBMA film. These results suggest that the water structure is very important factor to generate biocompatibility of polymers.",

keywords = "Biocompatibility, Carboxybetaine polymer, Structure of water",

author = "Susumu Tada and Takayuki Mori and Makoto Gemmei-Ide and Hiromi Kitano and Mitsuhiro Fukuda and Masaru Tanaka",

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language = "英語",

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note = "54th SPSJ Symposium on Macromolecules ; Conference date: 20-09-2005 Through 22-09-2005",

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TY - CONF

T1 - Correlation between the structure of water in the vicinity of carboxybetaine polymers and their biocompatibility

AU - Tada, Susumu

AU - Mori, Takayuki

AU - Gemmei-Ide, Makoto

AU - Kitano, Hiromi

AU - Fukuda, Mitsuhiro

AU - Tanaka, Masaru

PY - 2005

Y1 - 2005

N2 - Structure of water in the vicinity of carboxybetaine (CMB), n-buthyl methacrylate (BMA) polymers and their copolymers with various compositions was investigated by using vibrational spectroscopies. Raman spectroscopy has revealed that, in contrast with ordinary polyelectrolytes, the zwitterionic polymers, PCMB and water-soluble P(BMA/CMB), did not affect the hydrogen-bonded network structure of water in their aqueous solutions. ATR-IR spectra of water sorbed into the P(BMA/CMB) films was similar to that of free water, but that in PBMA film was not. The number of platelets adhered to the P(BMA/CMB) films was much smaller than that into PBMA film. These results suggest that the water structure is very important factor to generate biocompatibility of polymers.

AB - Structure of water in the vicinity of carboxybetaine (CMB), n-buthyl methacrylate (BMA) polymers and their copolymers with various compositions was investigated by using vibrational spectroscopies. Raman spectroscopy has revealed that, in contrast with ordinary polyelectrolytes, the zwitterionic polymers, PCMB and water-soluble P(BMA/CMB), did not affect the hydrogen-bonded network structure of water in their aqueous solutions. ATR-IR spectra of water sorbed into the P(BMA/CMB) films was similar to that of free water, but that in PBMA film was not. The number of platelets adhered to the P(BMA/CMB) films was much smaller than that into PBMA film. These results suggest that the water structure is very important factor to generate biocompatibility of polymers.

KW - Biocompatibility

KW - Carboxybetaine polymer

KW - Structure of water

UR - http://www.scopus.com/inward/record.url?scp=33645561559&partnerID=8YFLogxK

M3 - 学会論文

AN - SCOPUS:33645561559

SP - 3826

EP - 3827

T2 - 54th SPSJ Symposium on Macromolecules

Y2 - 20 September 2005 through 22 September 2005

ER -

Correlation between the structure of water in the vicinity of carboxybetaine polymers and their biocompatibility

Abstract

Conference

Keywords

ASJC Scopus subject areas

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