Comprehensive behavioral analysis of tryptophan 2,3-dioxygenase (Tdo2) knockout mice:

Keyphrases

• Knock-in Mouse Model 100%
• Behavior Analysis 100%
• Tryptophan 2,3-dioxygenase (TDO2) 100%
• Psychiatric Disorders 80%
• Behavioral Phenotype 60%
• Schizophrenia 40%
• Gene Deletion 40%
• Anxiety-like Behavior 40%
• Tryptophan 40%
• Behavioral Effects 40%
• Tryptophan Metabolism 40%
• Locomotor Activity 20%
• Statistical Significance 20%
• Dysregulation 20%
• Depressive-like Behavior 20%
• Inflammation 20%
• Rate-limiting Enzyme 20%
• Hippocampus 20%
• Neurological Disorders 20%
• Targeted Deletion 20%
• Single nucleotide Polymorphism 20%
• Midbrain 20%
• Prepulse Inhibition 20%
• Social Behavior 20%
• Genetic Studies 20%
• Inflammatory Conditions 20%
• Cognitive Performance 20%
• Serotonin 5-HT 20%
• 5-hydroxytryptamine 20%
• Stress Conditions 20%
• Degradative Enzymes 20%
• Indoleamine 2,3-dioxygenase 1 (IDO1) 20%
• Kynurenine 20%
• Activity Performance 20%
• Exploratory Activity 20%
• Abnormal Gait Pattern 20%
• Kynurenine Pathway 20%

Biochemistry, Genetics and Molecular Biology

• Enzyme 100%
• Gene Deletion 100%
• Knockout Mouse 100%
• Tryptophan Metabolism 100%
• Tryptophan 2,3-dioxygenase 100%
• Tryptophan 100%
• Genetics 50%
• Single-Nucleotide Polymorphism 50%
• Locomotion 50%
• Prepulse Inhibition 50%
• Indoleamine 2,3-dioxygenase 50%
• Kynurenine Pathway 50%
• Messenger RNA 50%
• Serotonin 50%
• Kynurenine 50%

Neuroscience

• Tryptophan 100%
• Tryptophan 2,3 Dioxygenase 100%
• Behavior (Neuroscience) 75%
• Metabolic Pathway 50%
• Behavioral Effect 50%
• Gene Deletion 50%
• Kynurenine 50%
• Locomotor Activity 25%
• Serotonin 25%
• Hippocampus 25%
• Midbrain 25%
• Single-Nucleotide Polymorphism 25%
• Prepulse Inhibition 25%
• Social Behavior 25%
• Neurological Disorder 25%
• Indoleamine 2,3 Dioxygenase 25%
• Messenger RNA 25%