Chromosomal Assignment of the Gene for Protein Tyrosine Phosphatase HPTPδ

Kiminori Hasegawa; Takeshi Ariyama; Johji Inazawa; Kazuya Mizuno; Mami Ogimoto; Tatsuo Katagiri; Hidetaka Yakura

doi:10.1111/j.1349-7006.1993.tb02825.x

Chromosomal Assignment of the Gene for Protein Tyrosine Phosphatase HPTPδ

Kiminori Hasegawa, Takeshi Ariyama, Johji Inazawa, Kazuya Mizuno, Mami Ogimoto, Tatsuo Katagiri, Hidetaka Yakura^*

^*Corresponding author for this work

Faculty of Liberal Arts and Sciences

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Protein tyrosine phosphatase (PTP) negatively regulates the effect of protein tyrosine kinases and is implicated in the regulation of a variety of biological phenomena such as cell activation, differentiation and neoplastic transformation. To gain insight into the role of PTPs, we cloned the human receptor‐type FTP gene and assigned the chromosome harboring the gene for HPTPδ by using DNAs from human‐mouse hybrid cell lines and by fluorescence in situ hybridization. The results clearly demonstrated that HPTPδ gene maps to human chromosome 9p24.

Original language	English
Pages (from-to)	1219-1222
Number of pages	4
Journal	Japanese Journal of Cancer Research
Volume	84
Issue number	12
DOIs	https://doi.org/10.1111/j.1349-7006.1993.tb02825.x
State	Published - 1993/12

Keywords

Chromosomal mapping
FISH
HPTPδ
Tumor suppressor gene

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1349-7006.1993.tb02825.x

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title = "Chromosomal Assignment of the Gene for Protein Tyrosine Phosphatase HPTPδ",

abstract = "Protein tyrosine phosphatase (PTP) negatively regulates the effect of protein tyrosine kinases and is implicated in the regulation of a variety of biological phenomena such as cell activation, differentiation and neoplastic transformation. To gain insight into the role of PTPs, we cloned the human receptor‐type FTP gene and assigned the chromosome harboring the gene for HPTPδ by using DNAs from human‐mouse hybrid cell lines and by fluorescence in situ hybridization. The results clearly demonstrated that HPTPδ gene maps to human chromosome 9p24.",

keywords = "Chromosomal mapping, FISH, HPTPδ, Tumor suppressor gene",

author = "Kiminori Hasegawa and Takeshi Ariyama and Johji Inazawa and Kazuya Mizuno and Mami Ogimoto and Tatsuo Katagiri and Hidetaka Yakura",

year = "1993",

month = dec,

doi = "10.1111/j.1349-7006.1993.tb02825.x",

language = "英語",

volume = "84",

pages = "1219--1222",

journal = "Japanese Journal of Cancer Research",

issn = "0910-5050",

publisher = "Oxford University Press",

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}

TY - JOUR

T1 - Chromosomal Assignment of the Gene for Protein Tyrosine Phosphatase HPTPδ

AU - Hasegawa, Kiminori

AU - Ariyama, Takeshi

AU - Inazawa, Johji

AU - Mizuno, Kazuya

AU - Ogimoto, Mami

AU - Katagiri, Tatsuo

AU - Yakura, Hidetaka

PY - 1993/12

Y1 - 1993/12

N2 - Protein tyrosine phosphatase (PTP) negatively regulates the effect of protein tyrosine kinases and is implicated in the regulation of a variety of biological phenomena such as cell activation, differentiation and neoplastic transformation. To gain insight into the role of PTPs, we cloned the human receptor‐type FTP gene and assigned the chromosome harboring the gene for HPTPδ by using DNAs from human‐mouse hybrid cell lines and by fluorescence in situ hybridization. The results clearly demonstrated that HPTPδ gene maps to human chromosome 9p24.

AB - Protein tyrosine phosphatase (PTP) negatively regulates the effect of protein tyrosine kinases and is implicated in the regulation of a variety of biological phenomena such as cell activation, differentiation and neoplastic transformation. To gain insight into the role of PTPs, we cloned the human receptor‐type FTP gene and assigned the chromosome harboring the gene for HPTPδ by using DNAs from human‐mouse hybrid cell lines and by fluorescence in situ hybridization. The results clearly demonstrated that HPTPδ gene maps to human chromosome 9p24.

KW - Chromosomal mapping

KW - FISH

KW - HPTPδ

KW - Tumor suppressor gene

UR - http://www.scopus.com/inward/record.url?scp=0027768599&partnerID=8YFLogxK

U2 - 10.1111/j.1349-7006.1993.tb02825.x

DO - 10.1111/j.1349-7006.1993.tb02825.x

M3 - 学術論文

C2 - 8294211

AN - SCOPUS:0027768599

SN - 0910-5050

VL - 84

SP - 1219

EP - 1222

JO - Japanese Journal of Cancer Research

JF - Japanese Journal of Cancer Research

IS - 12

ER -

Chromosomal Assignment of the Gene for Protein Tyrosine Phosphatase HPTPδ

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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