Chiral Sensing of Various Amino Acids Using Induced Circularly Polarized Luminescence from Europium(III) Complexes of Phenanthroline Dicarboxylic Acid Derivatives

Taka aki Uchida, Koichi Nozaki, Munetaka Iwamura*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Circularly polarized luminescence (CPL) was observed from [Eu(dppda)2] (dppda=4,7-diphenyl-1,10-phenanthroline-2,9-dicarboxylic acid) and [Eu(pzpda)2] (pzpda=pyrazino[2,3-f][1,10]phenanthroline-7,10-dicarboxylic acid) in aqueous solutions containing various amino acids. The selectivity of these complexes towards amino acids enabled them to be used as chiral sensors and their behavior was compared with that of [Eu(pda)2] (pda=1,10-phenanthroline-2,9-dicarboxylic acid). As these EuIII complexes have achiral D2d structures under ordinary conditions, there were no CPL signals in the emission assigned to f–f transitions. However, when the solutions contained particular amino acids they exhibited detectable CPL signals with glum values of about 0.1 (glum=CPL/2 TL; TL=total luminescence). On examining 13 amino acids with these three EuIII complexes, it was found that whether an amino acid induced a detectable CPL depended on the EuIII complex ligands. For example, when ornithine was used as a chiral agent, only [Eu(dppda)2] exhibited intense CPL in aqueous solutions of 10−2 mol dm−3. Steep amino acid concentration dependence suggested that CPL in [Eu(dppda)2] and [Eu(pzpda)2] was induced by the association of four or more amino acid molecules, whereas CPL in [Eu(pda)2] was induced by association of two arginine molecules.

Original languageEnglish
Pages (from-to)2415-2422
Number of pages8
JournalChemistry - An Asian Journal
Volume11
Issue number17
DOIs
StatePublished - 2016/09/06

Keywords

  • amino acids
  • chirality
  • lanthanides
  • luminescence
  • sensors

ASJC Scopus subject areas

  • General Chemistry
  • Biochemistry
  • Organic Chemistry

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