Characteristic fluorescence behavior of dialkynylpyrene derivatives in hydrophobic cavity of protein

Hideyuki Shinmori; Hirotoshi Furukawa; Kazuhisa Fujimoto; Hisao Shimizu; Masahiko Inouye; Toshifumi Takeuchi

doi:10.1246/cl.2009.84

Characteristic fluorescence behavior of dialkynylpyrene derivatives in hydrophobic cavity of protein

Hideyuki Shinmori, Hirotoshi Furukawa, Kazuhisa Fujimoto, Hisao Shimizu, Masahiko Inouye, Toshifumi Takeuchi^*

^*Corresponding author for this work

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Abstract

Water-soluble fluorescent molecules consisting of dialkynylpyrene skeleton with an oxyethylene unit were designed and synthesized for interacting with hydrophobic cavities of proteins. In the presence of serum albumin, the fluorescent spectra of dialkynylpyrene derivatives were remarkably changed. These behavior can be explained by monomer-excimer emission switching and twisted intramolecular charge-transfer mechanism.

Original language	English
Pages (from-to)	84-85
Number of pages	2
Journal	Chemistry Letters
Volume	38
Issue number	1
DOIs	https://doi.org/10.1246/cl.2009.84
State	Published - 2009

ASJC Scopus subject areas

General Chemistry

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title = "Characteristic fluorescence behavior of dialkynylpyrene derivatives in hydrophobic cavity of protein",

abstract = "Water-soluble fluorescent molecules consisting of dialkynylpyrene skeleton with an oxyethylene unit were designed and synthesized for interacting with hydrophobic cavities of proteins. In the presence of serum albumin, the fluorescent spectra of dialkynylpyrene derivatives were remarkably changed. These behavior can be explained by monomer-excimer emission switching and twisted intramolecular charge-transfer mechanism.",

author = "Hideyuki Shinmori and Hirotoshi Furukawa and Kazuhisa Fujimoto and Hisao Shimizu and Masahiko Inouye and Toshifumi Takeuchi",

year = "2009",

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AU - Shinmori, Hideyuki

AU - Furukawa, Hirotoshi

AU - Fujimoto, Kazuhisa

AU - Shimizu, Hisao

AU - Inouye, Masahiko

AU - Takeuchi, Toshifumi

PY - 2009

Y1 - 2009

N2 - Water-soluble fluorescent molecules consisting of dialkynylpyrene skeleton with an oxyethylene unit were designed and synthesized for interacting with hydrophobic cavities of proteins. In the presence of serum albumin, the fluorescent spectra of dialkynylpyrene derivatives were remarkably changed. These behavior can be explained by monomer-excimer emission switching and twisted intramolecular charge-transfer mechanism.

AB - Water-soluble fluorescent molecules consisting of dialkynylpyrene skeleton with an oxyethylene unit were designed and synthesized for interacting with hydrophobic cavities of proteins. In the presence of serum albumin, the fluorescent spectra of dialkynylpyrene derivatives were remarkably changed. These behavior can be explained by monomer-excimer emission switching and twisted intramolecular charge-transfer mechanism.

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DO - 10.1246/cl.2009.84

M3 - 学術論文

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VL - 38

SP - 84

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JO - Chemistry Letters

JF - Chemistry Letters

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ER -

Characteristic fluorescence behavior of dialkynylpyrene derivatives in hydrophobic cavity of protein

Abstract

ASJC Scopus subject areas

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