Case series of transcatherter edge-to-edge repair using MitraClip™system with Impella®mechanical circulatory support

Shuhei Tanaka; Teruhiko Imamura; Nikhil Narang; Atsuko Fukuo; Makiko Nakamura; Nobuyuki Fukuda; Hiroshi Ueno; Koichiro Kinugawa

doi:10.1093/ehjcr/ytac370

Case series of transcatherter edge-to-edge repair using MitraClip^™system with Impella^®mechanical circulatory support

Shuhei Tanaka, Teruhiko Imamura^*, Nikhil Narang, Atsuko Fukuo, Makiko Nakamura, Nobuyuki Fukuda, Hiroshi Ueno, Koichiro Kinugawa

^*Corresponding author for this work

Internal Medicine （2）

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Background: Secondary mitral regurgitation (SMR) is a major comorbidity in patients with heart failure with reduced ejection fraction (HFrEF). Transcatheter edge-to-edge repair (TEER) using the MitraClip™ system is a promising tool for selected patients with SMR and HFrEF. Durable success using this system in patients who have advanced heart failure and unsuitable anatomy remains a clinical challenge. Case summary: Three patients aged 67-72 years with HFrEF on inotropic support successfully underwent Impella®-assisted TEER at our centre. Following the procedure, two patients were able to be weaned off inotropic support and were discharged, while one patient expired during the index hospitalization. Discussion: Impella®-assisted TEER may be a feasible strategy for patients with SMR and HFrEF with unstable haemodynamics particularly when cardiac replacement therapy is not applicable.

Original language	English
Article number	ytac370
Journal	European Heart Journal - Case Reports
Volume	6
Issue number	9
DOIs	https://doi.org/10.1093/ehjcr/ytac370
State	Published - 2022/09/01

Keywords

Case report
Haemodynamics
Mechanical circulatory support
Mitral regurgitation
Valve disease

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Access to Document

10.1093/ehjcr/ytac370

Cite this

@article{613a49708e434acc9c7b68f6f2797a11,

title = "Case series of transcatherter edge-to-edge repair using MitraClip{\texttrademark}system with Impella{\textregistered}mechanical circulatory support",

abstract = "Background: Secondary mitral regurgitation (SMR) is a major comorbidity in patients with heart failure with reduced ejection fraction (HFrEF). Transcatheter edge-to-edge repair (TEER) using the MitraClip{\texttrademark} system is a promising tool for selected patients with SMR and HFrEF. Durable success using this system in patients who have advanced heart failure and unsuitable anatomy remains a clinical challenge. Case summary: Three patients aged 67-72 years with HFrEF on inotropic support successfully underwent Impella{\textregistered}-assisted TEER at our centre. Following the procedure, two patients were able to be weaned off inotropic support and were discharged, while one patient expired during the index hospitalization. Discussion: Impella{\textregistered}-assisted TEER may be a feasible strategy for patients with SMR and HFrEF with unstable haemodynamics particularly when cardiac replacement therapy is not applicable.",

keywords = "Case report, Haemodynamics, Mechanical circulatory support, Mitral regurgitation, Valve disease",

author = "Shuhei Tanaka and Teruhiko Imamura and Nikhil Narang and Atsuko Fukuo and Makiko Nakamura and Nobuyuki Fukuda and Hiroshi Ueno and Koichiro Kinugawa",

note = "Publisher Copyright: {\textcopyright} 2022 The Author(s). Published by Oxford University Press on behalf of the European Society of Cardiology.",

year = "2022",

month = sep,

day = "1",

doi = "10.1093/ehjcr/ytac370",

language = "英語",

volume = "6",

journal = "European Heart Journal - Case Reports",

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TY - JOUR

T1 - Case series of transcatherter edge-to-edge repair using MitraClip™system with Impella®mechanical circulatory support

AU - Tanaka, Shuhei

AU - Imamura, Teruhiko

AU - Narang, Nikhil

AU - Fukuo, Atsuko

AU - Nakamura, Makiko

AU - Fukuda, Nobuyuki

AU - Ueno, Hiroshi

AU - Kinugawa, Koichiro

PY - 2022/9/1

Y1 - 2022/9/1

N2 - Background: Secondary mitral regurgitation (SMR) is a major comorbidity in patients with heart failure with reduced ejection fraction (HFrEF). Transcatheter edge-to-edge repair (TEER) using the MitraClip™ system is a promising tool for selected patients with SMR and HFrEF. Durable success using this system in patients who have advanced heart failure and unsuitable anatomy remains a clinical challenge. Case summary: Three patients aged 67-72 years with HFrEF on inotropic support successfully underwent Impella®-assisted TEER at our centre. Following the procedure, two patients were able to be weaned off inotropic support and were discharged, while one patient expired during the index hospitalization. Discussion: Impella®-assisted TEER may be a feasible strategy for patients with SMR and HFrEF with unstable haemodynamics particularly when cardiac replacement therapy is not applicable.

AB - Background: Secondary mitral regurgitation (SMR) is a major comorbidity in patients with heart failure with reduced ejection fraction (HFrEF). Transcatheter edge-to-edge repair (TEER) using the MitraClip™ system is a promising tool for selected patients with SMR and HFrEF. Durable success using this system in patients who have advanced heart failure and unsuitable anatomy remains a clinical challenge. Case summary: Three patients aged 67-72 years with HFrEF on inotropic support successfully underwent Impella®-assisted TEER at our centre. Following the procedure, two patients were able to be weaned off inotropic support and were discharged, while one patient expired during the index hospitalization. Discussion: Impella®-assisted TEER may be a feasible strategy for patients with SMR and HFrEF with unstable haemodynamics particularly when cardiac replacement therapy is not applicable.

KW - Case report

KW - Haemodynamics

KW - Mechanical circulatory support

KW - Mitral regurgitation

KW - Valve disease

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