Biomarker of bone and cartilage destruction in rheumatoid arthritis

Shun Tanimura, Masaru Kato, Tatsuya Atsumi

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Recent progress in treatment and imaging enables us to aim the clinical remission in rheumatoid arthritis. In terms of achieving deep remission (structural remission) and predicting prognosis, useful serological biomarkers are now expected. Recently, some of the serological biomarkers, such as RANKL (receptor activator of NF-κB ligand) and TRACP (tartrate-resistant acid phopshatate)-5b, are used to assess the activity of rheumatoid arthritis. The levels of these biomarkers well reflect bone erosion but are less affected by age or physiological variation.

Original languageEnglish
Pages (from-to)1769-1775
Number of pages7
JournalClinical calcium
Volume25
Issue number12
StatePublished - 2015/12/01

ASJC Scopus subject areas

  • General Medicine

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