@inproceedings{432e63f3d7594f9e93471aab7c6923c1,
title = "Application of ball-lens hollow fiber Raman probe for studying anorectal prolapse",
abstract = "Our Raman probe that is called as ball-lens hollow fiber Raman probe (BHRP) had been proved possessing capability to detect the biochemical alteration within biological tissue. Whether BHRP has high capability and sensitivity in diagnosing the biochemical changing of tissue or not, mouse's normal rectal and anorectal prolapse (AP) were decided to be used as a model for this non invasive method. This AP is azoxymethane and DSS-induced mousea's anorectal prolapse. Main outcome of BHRP will be potential for non-invasive method in tumor diagnosing. BHRP spectra obtained were a high quality and allowed analysis of their differences between normal rectal (control group) and AP. After spectral acquisition and comparison with corresponding images of hematoxylin/eosinstained section observation used to make the histopathologic diagnosing, BHRP detected some differences within the region of moiety of DNA, protein (i.e. collagen) and lipid, then following with the alteration of symmetric P=O stretching vibration compared with the normal rectal tissue. BHRP discriminate normal tissue and AP in the real-time.",
keywords = "Anorectal prolapse, BHRP, Non-invasive, Raman spectroscopy, Symmetric P=O stretching vibration, Tumor",
author = "Andriana, {Bibin B.} and Akinori Taketani and Soeratman, {C. Linda R.} and Mika Ishigaki and Yasuhiro Maeda and Masanori Sawa and Hidetoshi Sato",
year = "2014",
doi = "10.1117/12.2037884",
language = "英語",
isbn = "9780819498519",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
booktitle = "Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV",
note = "Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XIV ; Conference date: 01-02-2014 Through 02-02-2014",
}