Analysis of ginsenosides in ginseng drugs using liquid chromatography- fourier transform ion cyclotron resonance mass spectrometry

Ken Tanaka*, Masayuki Kubota, Shu Zhu, Ushio Sankawa, Katsuko Komatsu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Analysis of ginsenosides in five Ginseng drugs derived from Pawa* ginseng (white ginseng), P. quinquefolius, P. japonicus produced in Japan, P. notoginseng, and P. vietnamensis using Liquid Chromatography-Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (LC-FTICR-MS) was performed. Ginsenosides in the drugs were identified by the molecular formula obtained from high-resolution mass data and multiple stage MS/MS analysis. Twenty-six known ginsenosides were identified as the major constituents in the extracts of the Ginseng drugs. The five Ginseng drugs showed different reconstructed mass chromatographic profiles and were discriminated from each other.

Original languageEnglish
Pages (from-to)625-632
Number of pages8
JournalNatural Product Communications
Volume2
Issue number6
DOIs
StatePublished - 2007

Keywords

  • Ginsenosides
  • LC-FTICR-MS
  • Panax
  • Saponins

ASJC Scopus subject areas

  • Pharmacology
  • Plant Science
  • Drug Discovery
  • Complementary and alternative medicine

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