An Clinical Study of the Furosemide VOR Test for the Endolymphatic Hydrops Diseases

The furosemide test is effective in the detection of endolymphatic hydrops (Futaki & Kitahara, 1971). However, this test is not easily performed because patients sometimes have nausea and vomiting. Instead of the caloric test, we used a furosemide VOR test, in which the pendular rotation test is performed before and after an i. v. injection of 20 mg of furosemide. Thirteen of 24 patients with Meniere's disease, four of six with delayed endolymphatic hydrops and one of two with syphilitic labyrinthitis had positive tests. These data suggest that endolymphatic hydrops may be easy to detect by the furosemide VOR test.