Amphibian prolactins: Activity in the eft skin transepithelial potential bioassay

Stephen C. Brown; Patricia Stocking Brown; Kazutoshi Yamamoto; Kouhei Matsuda; Sakae Kikuyama

doi:10.1016/0016-6480(91)90289-I

Amphibian prolactins: Activity in the eft skin transepithelial potential bioassay

Stephen C. Brown^*, Patricia Stocking Brown, Kazutoshi Yamamoto, Kouhei Matsuda, Sakae Kikuyama

^*Corresponding author for this work

Department of Biology

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

The effects of purified prolactins isolated from frogs (fPRL; Rana catesbeiana) and newts (nPRL; Cynops pyrrhogaster) were compared with those of ovine prolactin (oPRL) and thyrotropin releasing hormone (TRH) in the eft (Notophthalmus viridescens) skin transepithelial potential (TEP) bioassay. At total doses as low as 0.4 μg/animal, both fPRL and nPRL were as effective as oPRL in reducing eft skin TEP. By contrast, TRH at total doses as high as 400 μg/animal was ineffective in altering eft skin TEP. These data provide the first direct evidence that amphibian PRLs can exert significant physiological control over salamandrid integumental sodium transport.

Original language	English
Pages (from-to)	1-7
Number of pages	7
Journal	General and Comparative Endocrinology
Volume	82
Issue number	1
DOIs	https://doi.org/10.1016/0016-6480(91)90289-I
State	Published - 1991/04

ASJC Scopus subject areas

Animal Science and Zoology
Endocrinology

Access to Document

10.1016/0016-6480(91)90289-I

Cite this

@article{4a78e000b18e404ab071a263c9270b5f,

title = "Amphibian prolactins: Activity in the eft skin transepithelial potential bioassay",

abstract = "The effects of purified prolactins isolated from frogs (fPRL; Rana catesbeiana) and newts (nPRL; Cynops pyrrhogaster) were compared with those of ovine prolactin (oPRL) and thyrotropin releasing hormone (TRH) in the eft (Notophthalmus viridescens) skin transepithelial potential (TEP) bioassay. At total doses as low as 0.4 μg/animal, both fPRL and nPRL were as effective as oPRL in reducing eft skin TEP. By contrast, TRH at total doses as high as 400 μg/animal was ineffective in altering eft skin TEP. These data provide the first direct evidence that amphibian PRLs can exert significant physiological control over salamandrid integumental sodium transport.",

author = "Brown, {Stephen C.} and {Stocking Brown}, Patricia and Kazutoshi Yamamoto and Kouhei Matsuda and Sakae Kikuyama",

note = "Funding Information: This work was supported by NSF Grant DCB 85 17534 to P.S.B. and Grants-in-Aid from the Ministry of Education, Science and Culture of Japan to SK.",

year = "1991",

month = apr,

doi = "10.1016/0016-6480(91)90289-I",

language = "英語",

volume = "82",

pages = "1--7",

journal = "General and Comparative Endocrinology",

issn = "0016-6480",

publisher = "Academic Press Inc.",

number = "1",

}

TY - JOUR

T1 - Amphibian prolactins

T2 - Activity in the eft skin transepithelial potential bioassay

AU - Brown, Stephen C.

AU - Stocking Brown, Patricia

AU - Yamamoto, Kazutoshi

AU - Matsuda, Kouhei

AU - Kikuyama, Sakae

N1 - Funding Information: This work was supported by NSF Grant DCB 85 17534 to P.S.B. and Grants-in-Aid from the Ministry of Education, Science and Culture of Japan to SK.

PY - 1991/4

Y1 - 1991/4

N2 - The effects of purified prolactins isolated from frogs (fPRL; Rana catesbeiana) and newts (nPRL; Cynops pyrrhogaster) were compared with those of ovine prolactin (oPRL) and thyrotropin releasing hormone (TRH) in the eft (Notophthalmus viridescens) skin transepithelial potential (TEP) bioassay. At total doses as low as 0.4 μg/animal, both fPRL and nPRL were as effective as oPRL in reducing eft skin TEP. By contrast, TRH at total doses as high as 400 μg/animal was ineffective in altering eft skin TEP. These data provide the first direct evidence that amphibian PRLs can exert significant physiological control over salamandrid integumental sodium transport.

AB - The effects of purified prolactins isolated from frogs (fPRL; Rana catesbeiana) and newts (nPRL; Cynops pyrrhogaster) were compared with those of ovine prolactin (oPRL) and thyrotropin releasing hormone (TRH) in the eft (Notophthalmus viridescens) skin transepithelial potential (TEP) bioassay. At total doses as low as 0.4 μg/animal, both fPRL and nPRL were as effective as oPRL in reducing eft skin TEP. By contrast, TRH at total doses as high as 400 μg/animal was ineffective in altering eft skin TEP. These data provide the first direct evidence that amphibian PRLs can exert significant physiological control over salamandrid integumental sodium transport.

UR - http://www.scopus.com/inward/record.url?scp=0025801712&partnerID=8YFLogxK

U2 - 10.1016/0016-6480(91)90289-I

DO - 10.1016/0016-6480(91)90289-I

M3 - 学術論文

C2 - 1908395

AN - SCOPUS:0025801712

SN - 0016-6480

VL - 82

SP - 1

EP - 7

JO - General and Comparative Endocrinology

JF - General and Comparative Endocrinology

IS - 1

ER -

Amphibian prolactins: Activity in the eft skin transepithelial potential bioassay

Abstract

ASJC Scopus subject areas

Access to Document

Fingerprint

Cite this