A synthetic approach to discorhabdin alkaloids: Hypervalent iodine oxidation of p-substituted phenol derivatives to azacarbocyclic spirodienones

Yasuyuki Kita*, Takayuki Yakura, Hirofumi Tohma, Kazumi Kikuchi, Yasumitsu Tamura

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

105 Scopus citations

Abstract

Hypervalent iodine oxidation of O-silylated p-substituted phenols by phenyliodosyl bis (trifluoroacetate) (PIFA) in 2,2,2-trifluoroethanol gave azacarbocyclic spirodienones inn good yields.

Original languageEnglish
Pages (from-to)1119-1120
Number of pages2
JournalTetrahedron Letters
Volume30
Issue number9
DOIs
StatePublished - 1989

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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