A supramolecular DNA self-assembly based on β-cyclodextrin–adamantane complexation as a bioorthogonal sticky end motif

Junya Chiba; Ayumi Sakai; Syogo Yamada; Kazuhisa Fujimoto; Masahiko Inouye

doi:10.1039/c3cc43109f

A supramolecular DNA self-assembly based on β-cyclodextrin–adamantane complexation as a bioorthogonal sticky end motif

Junya Chiba^*, Ayumi Sakai, Syogo Yamada, Kazuhisa Fujimoto, Masahiko Inouye

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

We propose linear end-to-end assemblies of short DNA duplexes based on β-cyclodextrin–adamantane complexation. The assembled duplexes exhibited increased T _m values compared with those of the corresponding natural hybrids. Competition experiments with external guest molecules showed a substantial decrease in T _m of the terminal modified duplexes, suggesting the viability of inter-duplex complexation.

Original language	English
Pages (from-to)	6454-6456
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	57
DOIs	https://doi.org/10.1039/c3cc43109f
State	Published - 2013/06/20

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

Access to Document

10.1039/c3cc43109f

Cite this

@article{f523064c52d34b4c964f611a8429c527,

title = "A supramolecular DNA self-assembly based on β-cyclodextrin–adamantane complexation as a bioorthogonal sticky end motif",

abstract = "We propose linear end-to-end assemblies of short DNA duplexes based on β-cyclodextrin–adamantane complexation. The assembled duplexes exhibited increased T m values compared with those of the corresponding natural hybrids. Competition experiments with external guest molecules showed a substantial decrease in T m of the terminal modified duplexes, suggesting the viability of inter-duplex complexation.",

author = "Junya Chiba and Ayumi Sakai and Syogo Yamada and Kazuhisa Fujimoto and Masahiko Inouye",

year = "2013",

month = jun,

day = "20",

doi = "10.1039/c3cc43109f",

language = "英語",

volume = "49",

pages = "6454--6456",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "57",

}

TY - JOUR

T1 - A supramolecular DNA self-assembly based on β-cyclodextrin–adamantane complexation as a bioorthogonal sticky end motif

AU - Chiba, Junya

AU - Sakai, Ayumi

AU - Yamada, Syogo

AU - Fujimoto, Kazuhisa

AU - Inouye, Masahiko

PY - 2013/6/20

Y1 - 2013/6/20

N2 - We propose linear end-to-end assemblies of short DNA duplexes based on β-cyclodextrin–adamantane complexation. The assembled duplexes exhibited increased T m values compared with those of the corresponding natural hybrids. Competition experiments with external guest molecules showed a substantial decrease in T m of the terminal modified duplexes, suggesting the viability of inter-duplex complexation.

AB - We propose linear end-to-end assemblies of short DNA duplexes based on β-cyclodextrin–adamantane complexation. The assembled duplexes exhibited increased T m values compared with those of the corresponding natural hybrids. Competition experiments with external guest molecules showed a substantial decrease in T m of the terminal modified duplexes, suggesting the viability of inter-duplex complexation.

UR - http://www.scopus.com/inward/record.url?scp=84880874781&partnerID=8YFLogxK

U2 - 10.1039/c3cc43109f

DO - 10.1039/c3cc43109f

M3 - 学術論文

C2 - 23756493

AN - SCOPUS:84880874781

SN - 1359-7345

VL - 49

SP - 6454

EP - 6456

JO - Chemical Communications

JF - Chemical Communications

IS - 57

ER -

A supramolecular DNA self-assembly based on β-cyclodextrin–adamantane complexation as a bioorthogonal sticky end motif

Abstract

ASJC Scopus subject areas

Access to Document

Fingerprint

Cite this