A polymer-supported chiral dirhodium(II) complex: Highly durable and recyclable catalyst for asymmetric intramolecular C-H insertion reactions

Koji Takeda; Tadashi Oohara; Masahiro Anada; Hisanori Nambu; Shunichi Hashimoto

doi:10.1002/anie.201003730

A polymer-supported chiral dirhodium(II) complex: Highly durable and recyclable catalyst for asymmetric intramolecular C-H insertion reactions

Koji Takeda^*, Tadashi Oohara, Masahiro Anada, Hisanori Nambu, Shunichi Hashimoto

^*Corresponding author for this work

Synthetic and Biomolecular Organic Chemistry

Research output: Contribution to journal › Article › peer-review

100 Scopus citations

Abstract

A highly effective immobilization of [Rh2(S-PTTL)4] (PTTL=N-phthaloyl-tert- leucinate) has been achieved by copolymerization of monomer 1 with styrene and a flexible cross-linker. The immobilized catalyst promoted the title reaction at -78□°C with high enantioselectivity, and could be used for up to 100 cycles with a low level of leaching (0.28 ppm).

Original language	English
Pages (from-to)	6979-6983
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	49
Issue number	39
DOIs	https://doi.org/10.1002/anie.201003730
State	Published - 2010/09/17

Keywords

Asymmetric catalysis
C-H activation
Heterogeneous catalysis
Immobilization
Rhodium

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/anie.201003730

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title = "A polymer-supported chiral dirhodium(II) complex: Highly durable and recyclable catalyst for asymmetric intramolecular C-H insertion reactions",

abstract = "A highly effective immobilization of [Rh2(S-PTTL)4] (PTTL=N-phthaloyl-tert- leucinate) has been achieved by copolymerization of monomer 1 with styrene and a flexible cross-linker. The immobilized catalyst promoted the title reaction at -78□°C with high enantioselectivity, and could be used for up to 100 cycles with a low level of leaching (0.28 ppm).",

keywords = "Asymmetric catalysis, C-H activation, Heterogeneous catalysis, Immobilization, Rhodium",

author = "Koji Takeda and Tadashi Oohara and Masahiro Anada and Hisanori Nambu and Shunichi Hashimoto",

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T1 - A polymer-supported chiral dirhodium(II) complex

T2 - Highly durable and recyclable catalyst for asymmetric intramolecular C-H insertion reactions

AU - Takeda, Koji

AU - Oohara, Tadashi

AU - Anada, Masahiro

AU - Nambu, Hisanori

AU - Hashimoto, Shunichi

PY - 2010/9/17

Y1 - 2010/9/17

N2 - A highly effective immobilization of [Rh2(S-PTTL)4] (PTTL=N-phthaloyl-tert- leucinate) has been achieved by copolymerization of monomer 1 with styrene and a flexible cross-linker. The immobilized catalyst promoted the title reaction at -78□°C with high enantioselectivity, and could be used for up to 100 cycles with a low level of leaching (0.28 ppm).

AB - A highly effective immobilization of [Rh2(S-PTTL)4] (PTTL=N-phthaloyl-tert- leucinate) has been achieved by copolymerization of monomer 1 with styrene and a flexible cross-linker. The immobilized catalyst promoted the title reaction at -78□°C with high enantioselectivity, and could be used for up to 100 cycles with a low level of leaching (0.28 ppm).

KW - Asymmetric catalysis

KW - C-H activation

KW - Heterogeneous catalysis

KW - Immobilization

KW - Rhodium

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U2 - 10.1002/anie.201003730

DO - 10.1002/anie.201003730

M3 - 学術論文

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SN - 1433-7851

VL - 49

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EP - 6983

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 39

ER -

A polymer-supported chiral dirhodium(II) complex: Highly durable and recyclable catalyst for asymmetric intramolecular C-H insertion reactions

Abstract

Keywords

ASJC Scopus subject areas

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