A new compound from the rhizomes of boesenbergia pandurata

Truong Nhat Van Do, Hai Xuan Nguyen, Tho Huu Le, Trang My Thi Ngo, Phu Hoang Dang, Nghia Hieu Phung, Nghia Trong Vo, Duc Minh Nguyen, Nhan Hong Thi Le, Thanh Thanh Le, Mai Thanh Thi Nguyen, Suresh Awale, Nhan Trung Nguyen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Phytochemical investigation of the methanol extract of the rhizomes of Vietnamese Boesenbergia pandurata resulted in the isolation of a new secondary metabolite named panduratin P (1). The structure of this compound was elucidated by NMR spectroscopic analysis. Compound 1 exhibited a mild activity against PANC-1 human pancreatic cancer cell lines in nutrient-deprived medium (NDM) with PC50 value of 55.9 μM.

Original languageEnglish
Pages (from-to)739-740
Number of pages2
JournalNatural Product Communications
Volume13
Issue number6
DOIs
StatePublished - 2018/06

Keywords

  • Boesenbergia pandurata
  • PANC-1 cell
  • Secondary metabolite

ASJC Scopus subject areas

  • Drug Discovery
  • Complementary and alternative medicine
  • Plant Science
  • Pharmacology

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