A mutation (Trp¹¹⁹³→Leu¹¹⁹³) in the tyrosine kinase domain of the insulin receptor associated with type A syndrome of insulin resistance

Keyphrases

• Insulin Resistance 100%
• Insulin Receptor 100%
• Acanthosis Nigricans 100%
• Tyrosine Kinase Domain 100%
• Growth Factors 66%
• Insulin 66%
• Lymphocytes 66%
• Insulin-like 66%
• Insulin Receptor Gene 66%
• Diabetes 33%
• Insulin Sensitivity 33%
• Control Subjects 33%
• Autophosphorylation 33%
• Insulin Action 33%
• Type 1 Diabetes Mellitus (T1DM) 33%
• Biological Activity 33%
• Proband 33%
• Diabetic 33%
• Genomic DNA (gDNA) 33%
• Male Patients 33%
• Codon 33%
• Tyrosine Kinase Activity 33%
• Mild Reduction 33%
• Epstein-Barr Virus 33%
• Sequence Analysis 33%
• α-aminoisobutyric Acid 33%
• Insulin Binding 33%
• Thymidine Incorporation 33%
• Acid Accumulation 33%
• Cultured Fibroblasts 33%
• Hyperinsulinemic 33%
• Glucose Load 33%
• Type A Insulin Resistance 33%
• Exon 20 33%
• Phenotypic Appearance 33%

Medicine and Dentistry

• Insulin Resistance 100%
• Insulin Receptor 100%
• Protein Tyrosine Kinase 100%
• Acanthosis Nigricans 60%
• Somatomedin C 40%
• Receptor Gene 40%
• Lymphocyte 40%
• Diabetes 20%
• Diabetes Mellitus 20%
• Insulin Sensitivity 20%
• Receptor 20%
• Exon 20%
• Biological Activity 20%
• Genomic DNA 20%
• Codon 20%
• DNA Synthesis 20%
• Protein Sequencing 20%
• Sequence Analysis 20%
• Epstein Barr Virus 20%
• Insulin Binding 20%
• Autophosphorylation 20%
• 2 Amino 2 Methylpropionic Acid 20%
• Fibroblast 20%

Biochemistry, Genetics and Molecular Biology

• Insulin Resistance 100%
• Receptor Tyrosine Kinase 100%
• Tyrosine Kinase 100%
• Insulin Receptor 100%
• Receptor Gene 40%
• Insulin-Like Growth Factor 1 40%
• Lymphocyte 40%
• Insulin Sensitivity 20%
• Biological Activity 20%
• Exon 20%
• Proband 20%
• DNA Synthesis 20%
• Autophosphorylation 20%
• Codon 20%
• Epstein Barr Virus 20%
• Protein Sequencing 20%
• Insulin Binding 20%
• Fibroblast 20%
• Genomics 20%