A dearomative ipso-iodocyclization/desymmetrization sequence leading to optically active tricyclic piperazine scaffolds

Keyphrases

• Optically Active 100%
• Desymmetrization 100%
• Iodocyclization 100%
• Dearomative 100%
• Piperazine 100%
• Amino Acids 50%
• Spiro 50%
• Azaspiro 50%
• Chiral Center 50%
• Trien 50%
• Diastereoselective 50%
• Toxic Products 50%
• Synthetic Applications 50%
• Cyclohexadienones 50%
• Aza-Michael Addition 50%

Chemistry

• Piperazine 100%
• Toxic 50%
• Aza-Michael Addition 50%
• Amino Acid 50%