A case of sinonasal rhabdomyosarcoma in an elderly man

Hirohiko Tachino; Hideo Shojaku; Hiroshi Nishida; Yukio Watanabe; Yoko Ishii; Satsuki Yasumura; Yasuo Takano; Junya Fukuoka

doi:10.5631/jibirinsuppl.134.70

A case of sinonasal rhabdomyosarcoma in an elderly man

Hirohiko Tachino^*, Hideo Shojaku, Hiroshi Nishida, Yukio Watanabe, Yoko Ishii, Satsuki Yasumura, Yasuo Takano, Junya Fukuoka

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

We report a case of sinonasal rhabdomyosarcoma in an elderly 74-year-old man who complained of double vision and exophthalmos of the left eye. Computed tomography of the paranasal sinus confirmed findings of opacification of the left maxillary and ethmoidal sinuses extending into the orbit. Immunohistochemical examination of the excised tissue of the sinonasal tumor revealed the alveolar type of the rhabdomyosarcoma. Partial remission of the tumor was acquired in response to standard chemoradiotherapy for the rhabdomyosarcoma. However, the patient died due to multiple metastases 16 months after the onset of the disease. Sinonasal rhabdomyosarcoma with a high proliferative index (immunoexpression of MIB-1) has a poor prognosis.

Original language	English
Pages (from-to)	70-75
Number of pages	6
Journal	Practica Otologica, Supplement
Issue number	134
DOIs	https://doi.org/10.5631/jibirinsuppl.134.70
State	Published - 2012

Keywords

Adult
MIB-1
Nasal cavity
Prognosis
Rhabdomyosarcoma

ASJC Scopus subject areas

Otorhinolaryngology

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10.5631/jibirinsuppl.134.70

Cite this

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title = "A case of sinonasal rhabdomyosarcoma in an elderly man",

abstract = "We report a case of sinonasal rhabdomyosarcoma in an elderly 74-year-old man who complained of double vision and exophthalmos of the left eye. Computed tomography of the paranasal sinus confirmed findings of opacification of the left maxillary and ethmoidal sinuses extending into the orbit. Immunohistochemical examination of the excised tissue of the sinonasal tumor revealed the alveolar type of the rhabdomyosarcoma. Partial remission of the tumor was acquired in response to standard chemoradiotherapy for the rhabdomyosarcoma. However, the patient died due to multiple metastases 16 months after the onset of the disease. Sinonasal rhabdomyosarcoma with a high proliferative index (immunoexpression of MIB-1) has a poor prognosis.",

keywords = "Adult, MIB-1, Nasal cavity, Prognosis, Rhabdomyosarcoma",

author = "Hirohiko Tachino and Hideo Shojaku and Hiroshi Nishida and Yukio Watanabe and Yoko Ishii and Satsuki Yasumura and Yasuo Takano and Junya Fukuoka",

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doi = "10.5631/jibirinsuppl.134.70",

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T1 - A case of sinonasal rhabdomyosarcoma in an elderly man

AU - Tachino, Hirohiko

AU - Shojaku, Hideo

AU - Nishida, Hiroshi

AU - Watanabe, Yukio

AU - Ishii, Yoko

AU - Yasumura, Satsuki

AU - Takano, Yasuo

AU - Fukuoka, Junya

PY - 2012

Y1 - 2012

N2 - We report a case of sinonasal rhabdomyosarcoma in an elderly 74-year-old man who complained of double vision and exophthalmos of the left eye. Computed tomography of the paranasal sinus confirmed findings of opacification of the left maxillary and ethmoidal sinuses extending into the orbit. Immunohistochemical examination of the excised tissue of the sinonasal tumor revealed the alveolar type of the rhabdomyosarcoma. Partial remission of the tumor was acquired in response to standard chemoradiotherapy for the rhabdomyosarcoma. However, the patient died due to multiple metastases 16 months after the onset of the disease. Sinonasal rhabdomyosarcoma with a high proliferative index (immunoexpression of MIB-1) has a poor prognosis.

AB - We report a case of sinonasal rhabdomyosarcoma in an elderly 74-year-old man who complained of double vision and exophthalmos of the left eye. Computed tomography of the paranasal sinus confirmed findings of opacification of the left maxillary and ethmoidal sinuses extending into the orbit. Immunohistochemical examination of the excised tissue of the sinonasal tumor revealed the alveolar type of the rhabdomyosarcoma. Partial remission of the tumor was acquired in response to standard chemoradiotherapy for the rhabdomyosarcoma. However, the patient died due to multiple metastases 16 months after the onset of the disease. Sinonasal rhabdomyosarcoma with a high proliferative index (immunoexpression of MIB-1) has a poor prognosis.

KW - Adult

KW - MIB-1

KW - Nasal cavity

KW - Prognosis

KW - Rhabdomyosarcoma

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JO - Practica Otologica, Supplement

JF - Practica Otologica, Supplement

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ER -

A case of sinonasal rhabdomyosarcoma in an elderly man

Abstract

Keywords

ASJC Scopus subject areas

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