A case of refractory chronic respiratory tract infection due to pseudomonas aeruginosa successfully controlled by combination of clarithromycin and azithromycin

Yoshihiro Yamamoto; Koichi Izumikawa; Naoki Hosogaya; Yoshitomo Morinaga; Shigeki Nakamura; Yoshifumi Imamura; Taiga Miyazaki; Noriho Sakamoto; Yuji Ishimatu; Hiroshi Kakeya; Katsunori Yanagihara; Akira Yasuoka; Shigeru Kohno

doi:10.2169/internalmedicine.51.6985

A case of refractory chronic respiratory tract infection due to pseudomonas aeruginosa successfully controlled by combination of clarithromycin and azithromycin

Yoshihiro Yamamoto, Koichi Izumikawa^*, Naoki Hosogaya, Yoshitomo Morinaga, Shigeki Nakamura, Yoshifumi Imamura, Taiga Miyazaki, Noriho Sakamoto, Yuji Ishimatu, Hiroshi Kakeya, Katsunori Yanagihara, Akira Yasuoka, Shigeru Kohno

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The prognosis of patients with chronic respiratory tract infections, especially diffuse panbronchiolitis, is remarkably improved by long-term administration of low-dose macrolides. However, in some cases, patients are refractory to macrolide treatment and show a low or no response; therefore, new treatment strategies are required. Here we present a patient refractory to either single low-dose clarithromycin or azithromycin but responded remarkably to the combination usage of both macrolides.

Original language	English
Pages (from-to)	1383-1386
Number of pages	4
Journal	Internal Medicine
Volume	51
Issue number	11
DOIs	https://doi.org/10.2169/internalmedicine.51.6985
State	Published - 2012

Keywords

Azithromycin
Chronic respiratory tract infection
Clarithromycin
Pseudomonas aeruginosa

ASJC Scopus subject areas

Internal Medicine

Access to Document

10.2169/internalmedicine.51.6985

Cite this

Yamamoto, Y., Izumikawa, K., Hosogaya, N., Morinaga, Y., Nakamura, S., Imamura, Y., Miyazaki, T., Sakamoto, N., Ishimatu, Y., Kakeya, H., Yanagihara, K., Yasuoka, A., & Kohno, S. (2012). A case of refractory chronic respiratory tract infection due to pseudomonas aeruginosa successfully controlled by combination of clarithromycin and azithromycin. Internal Medicine, 51(11), 1383-1386. https://doi.org/10.2169/internalmedicine.51.6985

@article{efa3e9fb395341289f33bbcf05b76efd,

title = "A case of refractory chronic respiratory tract infection due to pseudomonas aeruginosa successfully controlled by combination of clarithromycin and azithromycin",

abstract = "The prognosis of patients with chronic respiratory tract infections, especially diffuse panbronchiolitis, is remarkably improved by long-term administration of low-dose macrolides. However, in some cases, patients are refractory to macrolide treatment and show a low or no response; therefore, new treatment strategies are required. Here we present a patient refractory to either single low-dose clarithromycin or azithromycin but responded remarkably to the combination usage of both macrolides.",

keywords = "Azithromycin, Chronic respiratory tract infection, Clarithromycin, Pseudomonas aeruginosa",

author = "Yoshihiro Yamamoto and Koichi Izumikawa and Naoki Hosogaya and Yoshitomo Morinaga and Shigeki Nakamura and Yoshifumi Imamura and Taiga Miyazaki and Noriho Sakamoto and Yuji Ishimatu and Hiroshi Kakeya and Katsunori Yanagihara and Akira Yasuoka and Shigeru Kohno",

year = "2012",

doi = "10.2169/internalmedicine.51.6985",

language = "英語",

volume = "51",

pages = "1383--1386",

journal = "Internal Medicine",

issn = "0918-2918",

publisher = "Japanese Society of Internal Medicine",

number = "11",

}

Yamamoto, Y, Izumikawa, K, Hosogaya, N, Morinaga, Y, Nakamura, S, Imamura, Y, Miyazaki, T, Sakamoto, N, Ishimatu, Y, Kakeya, H, Yanagihara, K, Yasuoka, A & Kohno, S 2012, 'A case of refractory chronic respiratory tract infection due to pseudomonas aeruginosa successfully controlled by combination of clarithromycin and azithromycin', Internal Medicine, vol. 51, no. 11, pp. 1383-1386. https://doi.org/10.2169/internalmedicine.51.6985

TY - JOUR

T1 - A case of refractory chronic respiratory tract infection due to pseudomonas aeruginosa successfully controlled by combination of clarithromycin and azithromycin

AU - Yamamoto, Yoshihiro

AU - Izumikawa, Koichi

AU - Hosogaya, Naoki

AU - Morinaga, Yoshitomo

AU - Nakamura, Shigeki

AU - Imamura, Yoshifumi

AU - Miyazaki, Taiga

AU - Sakamoto, Noriho

AU - Ishimatu, Yuji

AU - Kakeya, Hiroshi

AU - Yanagihara, Katsunori

AU - Yasuoka, Akira

AU - Kohno, Shigeru

PY - 2012

Y1 - 2012

N2 - The prognosis of patients with chronic respiratory tract infections, especially diffuse panbronchiolitis, is remarkably improved by long-term administration of low-dose macrolides. However, in some cases, patients are refractory to macrolide treatment and show a low or no response; therefore, new treatment strategies are required. Here we present a patient refractory to either single low-dose clarithromycin or azithromycin but responded remarkably to the combination usage of both macrolides.

AB - The prognosis of patients with chronic respiratory tract infections, especially diffuse panbronchiolitis, is remarkably improved by long-term administration of low-dose macrolides. However, in some cases, patients are refractory to macrolide treatment and show a low or no response; therefore, new treatment strategies are required. Here we present a patient refractory to either single low-dose clarithromycin or azithromycin but responded remarkably to the combination usage of both macrolides.

KW - Azithromycin

KW - Chronic respiratory tract infection

KW - Clarithromycin

KW - Pseudomonas aeruginosa

UR - http://www.scopus.com/inward/record.url?scp=84863099114&partnerID=8YFLogxK

U2 - 10.2169/internalmedicine.51.6985

DO - 10.2169/internalmedicine.51.6985

M3 - 学術論文

C2 - 22687847

AN - SCOPUS:84863099114

SN - 0918-2918

VL - 51

SP - 1383

EP - 1386

JO - Internal Medicine

JF - Internal Medicine

IS - 11

ER -

A case of refractory chronic respiratory tract infection due to pseudomonas aeruginosa successfully controlled by combination of clarithromycin and azithromycin

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Fingerprint

Cite this